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BackgroundGiant cell fibroma (GCF) is a rare benign oral fibrous lesion which is predominantly found in the mandible of Caucasians but rarely in the maxilla and black population above the third decade of life. Objective: To draw the attention of clinicians to a rare, late and unusually large presentation of Giant Cell Fibroma Case report: The index case was a 68-year-old fisherwoman with a ten-year-old slow-growing painless swelling occupying the left anterior maxilla. The lesion crossed the midline to the right causing incompetent lips and teeth displacement leading to aesthetics and functional problems. Upon clinical examination, a provisional diagnosis of peripheral giant cell granuloma was made. Radiological essentially revealed a soft tissue mass, histopathological evaluations confirmed the diagnosis of GCF and the patient was prepared for surgical excision. A surgical excision of the soft tissue mass and peripheral ostectomy was performed. Conclusion: GCF has distinct histopathologic features occurring in any age, race, site and decades of life; growing very large causing aesthetics and functional problems. Immunohistochemistry if available is an additional resource to unequivocally establish the diagnosis.

This study aims to report seven cases of congenital granular cell epulis (CGCE) diagnosed in four teaching hospitals in Southwestern Nigeria over a period of 8 years. CGCE is a rare lesion that presents exclusively at birth. It is benign, but often presents an unsightly appearance, and may be associated with difficulty in feeding, thus early presentation of cases for treatment. The records of the oral and maxillofacial pathology departments of four Nigerian teaching hospitals were assessed for lesions with histological diagnosis of CGCE. Data inclusive of age, gender, anatomic site, and mode of treatment was retrieved and analyzed with SPSS version 21. Seven cases were identified from the four teaching hospitals. All cases occurred in females with an average period of presentation at 7 days after birth. Most of the cases (71.4%) occurred on the maxillary alveolar ridge. Six cases presented as a single pedunculated or sessile lesion, while in one case, three nodules were seen. Although spontaneous regression has been documented in literature, all our cases had surgical excision under local anesthesia without complications or recurrence. All our cases were diagnosed in females and 71.4% were on the maxillary alveolar ridge.

The aim of this study was to report an unusual presentation of mucoepidermoid carcinoma (MEC) on the dorsum of tongue and to add to the body of knowledge on the various sites of occurrence of the lesion. MEC is a malignant, locally invasive tumor of salivary glands composed of varying proportions of mucussecreting and squamous cells, with the presence of intermediate cell differentiation between these other two cell types. More than half of reported cases involve major salivary glands and it is seen rarely on the dorsum of tongue. We present an unusual case of a low-grade MEC on the dorsum of tongue of a 40-year-old man. Discussion on clinical and microscopic types and immunohistochemical features of this tumor is presented in relation to pertinent literature. Biologic behavior and clinical manifestations of MEC usually correlate with its histological grade, which are required for appropriate treatment.

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