Introduction: Epilepsy is one of the most prevalent primary central nervous system diseases in the world. This pathology is classified into two principal axes: topographic and etiological. In most cases, the diagnosis of an epileptic seizure can be made clinically by obtaining a detailed history and general physical examination, with neurological and psychiatric emphasis. Methods: This is the literature review study, whose bibliographic research was carried out in Pubmed, Scopus, Scielo and Epileptic Seizures: the challenge continues

Despite the diagnostic and therapeutic advances, intraparenchymal hemorrhage (HIP) continues to present high Indices of mortality and disability. Its clinical differentiation with ischemic stroke from neuroimaging examination is fundamental. There is no specific treatment for a HIP. Its management consists of support and approach measures on intracranial hypertension, being reserved for the intervention Surgical in selected cases. Minimally invasive surgical techniques are underway. This study aims to review and discuss the approach of intraparenchymatous hemorrhages in medical practice.

To address, in a practical way, the acute treatment of ischemic cerebrovascular accident (CVA) based on the scientific recommendations latest. Methods: A bibliographic search was performed in the PubMed, Scopus, Scielo and Uptodate database from January/2012 to April/2018, using the descriptors "stroke", "early management", "therapeutic", "intravenous thrombolysis", "combined treatment", "mechanical thrombectomy" and its combinations. The selection of the articles was made by listing those of greater relevance according to the proposed theme, both in the foreign and Brazilian literature, in a nonsystematic way. Results: Intravenous thrombolysis with recombinant tissue plasminogen activator (rtPA) within 4.5 hours of onset of symptoms is considered the therapy of choice in eligible patients. According to the new guidelines, mechanical thrombectomy can be performed within 24h and, for prevention of subsequent ischemic events, revascularization between 48h and seven days of the index event in candidate patients is reasonable. Conclusions: As an essential cause of death and disability in the world, acute ischemic stroke treatment has advanced rapidly in recent years, improving therapeutic methods and their combinations. In clinical practice, recognizing, stratifying and listing, quickly and effectively, the best therapy for stroke patients is paramount.

Despite advances in the treatment of subarachnoid hemorrhage, morbimortality rates remain elevated. Patients who have a sudden onset headache followed or not by altered consciousness, require a high degree of suspicion for the appropriate diagnosis in the emergency room. Those with lighter symptoms, presence of headache without other neurological alterations are the most susceptible to diagnostic error. All should be evaluated quickly, receiving specialized neurointensive care and ear

The fibers in the peripheral nervous system are frequent targets of injuries, being distributed throughout the length of the body. Such lesions culminate in motor, sensory and autonomic changes, thus recent evidence shows the influence ideal environment for growth of nerve fibers damaged in the Central Nervous System (CNS). Our objective was to verify this cell behavior in the central sphere, analyzing cellular plasticity of the spinal cord (SC) in the presence of sciatic nerve-conditioned medium (SNCM) from neonatal rats. 12 animals were used, 06 of those aged 45 days, and the other 06 aged 02 days, and it was Sciatic nerve-conditioned medium promotes trophic induction in spinal cord cultured cells