Nasal and paranasal lymphomas usually present an intricate diagnostic challenge considering its lack of specifi c signs and symptoms. In Indian setup patients usually present in late stages of the disease. Brain involvement leads to the treatment being unfruitful as the patient deteriorates were fast. We are presenting our 12-year-old tribal patient's case details in whom the terminal stage of presentation led to convulsions, respiratory failure and death. Delay in pathological and immunohistochemistry diagnosis probably also was a factor leading to delay in starting chemotherapy. Diagnostic and treatment dilemmas considering the patients socioeconomic class and general nutrition and health are also considered.
Juvenile nasopharyngeal angiofibroma (JNA) is locally destructive benign vascular tumor for which surgical excision has always been the treatment of choice, in spite of the availability of various other treatment modalities. Complete removal at the maiden attempt has always been the key to a successful outcome. Recurrences (or rather residuals) discourage both the surgeon and patient.
This prospective study was carried out in the Department of Otorhinolaryngology, Sir Sayajirao General Hospital, Vadodara, Gujarat, between August 2002 and 2015. We have studied 28 patients with JNA for growth patterns, histological characteristics and to compare various surgical modalities. Besides other investigations a detailed histological examination of the tumor was performed which suggested that as the tumor ages, the stroma predominates and the vessels are compressed into slits. In actively growing tumor the vascular component predominates. The percentage of open vascular channels is directly proportional to the bleeding while the intervascular fibrosis is inversely related. Surgical excision of JNA is the preferred modality of treatment. Surgical approach is sometimes the most tricky decision. Choosing the right approach is akin to walking on the thin rope with adequate exposure on one side and postoperative scar on the other.
How to cite this article
Thapar T, Gupta RR, Jagtap PJ, Aiyer RG. Juvenile Nasopharyngeal Angiofibroma: Correlating Histology, Surgical Approach and Blood Loss. Clin Rhinol An Int J 2015;8(2):47-52.
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