Introducción: El sueño es importante para el correcto desempeño del individuo, participa en muchos procesos biológicos. Los estudiantes de medicina frecuentemente no duermen la cantidad recomendada de horas de sueño por día. Esto afecta a su calidad de sueño, con repercusiones en su calidad de vida. Objetivo: Identificar la asociación entre la calidad del sueño según el cuestionario Pittsburgh Sleep Quality Index (PSQI) y la calidad de vida según el cuestionario The World Health Organization Quality of Life (WHOQOL–BREF) de la Organización Mundial de la Salud (OMS), y describir los factores de riesgo más prevalentes para trastornos de sueño en estudiantes de Medicina de la Universidad Católica Santiago de Guayaquil (UCSG). Métodos: Estudio observacional transversal en estudiantes de Medicina de la UCSG. Resultados: Las encuestas fueron completadas por 211 estudiantes, la media de edad fue 20,8±2,6 años; el 62,1% eran mujeres. La media de IMC fue de 23,1±3,8, el 20,4% de los estudiantes tenía sobrepeso; y el 4,3% tenía obesidad. La puntuación media en el PSQI obtenida en la población estudiada fue de 7,2±3,1; y en el WHOQOL-BREF fue de 60,9%. El coeficiente de correlación de Pearson, r2, entre ambas variables fue de –0.33 (p: <0.01). Conclusión: La mala calidad de sueño guarda una correlación inversa con la calidad de vida. El dominio de calidad de vida más asociado a mala calidad de sueño fue el dominio físico. El factor de riesgo para mala calidad de sueño más frecuente fue la roncopatía. Palabras clave: calidad, estudiantes, medicina, Pittsburgh Sleep Quality Index, Sueño, WHOQOL- BREF
Coronavirus disease 2019 pandemic has spread rapidly to the world. The disease can vary from mild cases to severe respiratory distress; this may increase rapidly and overwhelm the pediatric intensive care units. Lately, there have been various reports about a de novo multisystem inflammatory syndrome in children or pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 infection. We classified the disease into 2 spectrums: the acute phase in severely ill patients and the postinflammatory phase. Neither of them could be classified as mild because there is enough evidence that supports a wide range of complications. The goals of this brief review were to summarize available literature and to give some awareness about the current status of the coronavirus disease 2019 in the severely ill patients during the active phase and postinflammatory phase.
Early infantile epileptic encephalopathies (EIEEs) constitute a group of severe early onset epilepsies. Although still classified under syndromic clusters of clinical features, the genetic basis of several EIEEs leads to the definition of new types of epilepsies. We report a newborn male with seizures since his second day of life. The results of the first line diagnostic tests did not identify the cause of the seizures, which prompted a genetic study. A de novo KCNQ2 genomic variant that may explain the neonatal epileptic encephalopathy was found and led to more appropriate treatment. Genetic testing allows more specific treatment and more accurate prognosis, and also adds to the database of the phenotypes associated with the genomic variants.
On December 30, 2019, the first reports of a group of patients with unknown etiology pneumonia appeared in Wuhan city, Hubei province, China. Taking into consideration the large amount of similar nucleotide sequences between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the past epidemic coronavirus, it will be appropriate to expect that such pathogens share the same cell line tropism and systemic pathology. Although several studies have, so far, identified the clinical characteristics of COVID-19 cases, there is very little knowledge on the extrapulmonary affection of SARS-CoV-2. In this review, we summarize reports of the main affected organs besides the pulmonary system such as the liver and kidneys, as well as the cardiovascular and nervous system. The mechanisms of lesion remain largely unclear. The approach of this investigation is to suggest multisystemic work-up in patients with SARS-CoV-2 infection, aside from its respiratory management.
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