Epithelial-myoepithelial carcinomas are a rare form of salivary gland carcinoma. They are found predominantly in the parotid glands and rarely occur in the upper airway and in minor salivary glands. These neoplasms are found predominantly in women in the seventh and eighth decades of life and account for less than 1% of all salivary gland ductal carcinomas. These tumors may demonstrate infiltrative and destructive patterns, with a tendency to metastasize. It is recommended that they be approached and treated along the same avenues as any other malignant lesions of the head and neck.
Sweet syndrome (acute febrile neutrophilic dermatosis) is a disorder of unknown etiology. It has been associated with autoimmune processes, malignancies, infections, drug reactions, and gastrointestinal disorders such as inflammatory bowel disease. We describe the case of a 51-yearold man who presented with severe pain in his tongue and throat and referred pain in his right ear, along with odynophagia, fever, and hoarseness of 48 hours' duration. An oral and oropharyngeal examination revealed the presence of aphthous ulcerations, as well as a 3 × 3-cm raised inflammatory lesion on the right anterior lateral tongue and a 5 × 5-mm bulla on the hard palate in the midline. In addition, erythematous papules and macules were noted on his face, neck, and extremities. Cultures, a biopsy, and laboratory tests yielded a diagnosis of Sweet syndrome. The patient was prescribed oral prednisone, and his signs and symptoms resolved within 2 months. Although Sweet syndrome is uncommon, even in dermatology practice, its head and neck and oral manifestations and its association with paraneoplastic disease warrant the need for otolaryngologists to be aware of the condition.
Sweet syndrome (acute f ebrile neutrophilic dermatosis) is a disorder of unknown etiology. It has been associated withautoimmuneprocesses, malignancies, infections, drug reactions, and gastrointestinal disorders suchas inflammatory bowel disease. Wedescribe the case of a 51-yearold man who presented with severe pain in his tongue and throatand referred pain in his rightear, alongwith odynophagia.fever; and hoarsenessof 48 hours'duration. An oral and oropharyngeal examination revealed the presence of aphthous ulcerations, as wellas a 3 x 3-cm raised inflammatory lesion on the right anterior lateral tongue and a 5 x 5-mm bulla on the hard palate in the . midline. In addition, erythematous papules and macules were notedon hisface, neck, and extremities. Cultures, a biopsy, and laboratory tests yielded a diagnosis of Sweet syndrome. The patient was prescribed oral prednisone, and his signs and symptoms resolved within 2 months. AlthoughSweetsyndrome is uncommon, even in dermatology practice, itsheadand neckand oral manifestations and its association with paraneoplastic disease warrant theneedfor otolaryngologists tobeaware ofthecondition.
The current status and implications of the neurohumoral hypothesis of motion-induced vomiting are reviewed. Data show that squirrel monkey subjects vomit only once if horizontal rotation is terminated immediately on the occurrence of the emetic response. Refractory periods for multiple vomiting episodes concurrent with continued rotation are sufficiently brief to suggest that the expected presence of the hypothetical neurochemical agent in the cerebrospinal fluid of the fourth ventricle should continue to evoke more than one vomiting response even after cessation of motion stimulation. In its present form, the hypothesis is conceptually vague and should be developed further to account for a mechanism by which the expected recurrent emesis is inhibited during the period when the alleged agent is a potentially effective stimulant.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.