Anti-D causing mild hemolytic anemia was found in the serum and on the red cells of a D-positive patient who had received a kidney transplant from his D-negative mother. Anti-D had been detected in the donor's serum before transplantation. Gm allotyping of the patient's serum, donor's serum, donor's anti-D, and the unexpected anti-D in the posttransplantation serum showed the antibody to be of maternal origin. The patient was Gm(fb), the donor Gm(agfb), the maternal anti-D Gm (afb), and the anti-D in the posttransplantation serum was Gm(a).
Alloantibodies of A and B specificity were detected in the serum and on the red cells of 4 non-0
recipients of group 0 solid organ transplants. The antibodies were assumed to be produced by ‘passenger’ lymphocytes
introduced at the time of transplant. Gm allotyping of donor serums, recipient serums and the unexpected
antibodies was done. Gm typing was informative in 1 case, when the anti-A(1) found in the serum of a liver transplant
recipient was shown to be of phenotype Gm(fb) and the Gm phenotype of the recipient to be Gm(axg). Gm allotyping
was not informative in the other 3 cases.
Alloantibodies of A and B specificity were detected in the serum and on the red cells of 4 non-0 recipients of group 0 solid organ transplants. The antibodies were assumed to be produced by 'passenger' lymphocytes introduced at the time of transplant. Gm allotyping of donor serums, recipient serums and the unexpected antibodies was done. Gm typing was informative in 1 case, when the anti-A1 found in the serum of a liver transplant recipient was shown to be of phenotype Gm(fb) and the Gm phenotype of the recipient to be Gm(axg). Gm allotyping was not informative in the other 3 cases.
Anti-D causing mild hemolytic anemia was found in the serum and on the red cells of a D-positive
patient who had received a kidney transplant from his D-negative mother. Anti-D had been detected in the donor’s
serum before transplantation. Gm allotyping of the patient’s serum, donor’s serum, donor’s anti-D, and the unexpected
anti-D in the posttransplantation serum showed the antibody to be of maternal origin. The patient was
Gm(fb), the donor Gm(agfb), the maternal anti-D Gm (afb), and the anti-D in the posttransplantation serum was
Gm(a).
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