The phospholipid fatty acid composition of Amphimedoncompressa was reinvestigated and the 2-methoxyhexadecanoic acid was identified for the first time in nature. Structure characterization was accomplished by means of gas chromatography-mass spectrometry and total synthesis from commercially available 2-hydroxyhexadecanoic acid.

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1999ketones ketones (benzene compounds) Q 0350 -079N-tert-Butyldimethylsilyl Imines as Intermediates for the Synthesis of Amines and Ketones.-Addition of Grignard or organolithium reagents to benzonitrile and subsequent reaction with a chlorosilane affords the corresponding N-silylimines [cf. (III)], which provide the desired phenylalkylamines [cf. (IV), (VI)] after reduction with borane reagents. Enantioselective reduction of these N-silylimines using chiral borane reagents derived from norephedrine or (S)-2-amino1,1,2-triphenylethanol provides chiral phenylalkylamines such as (VIII) with modest to good enantiomeric excess. Hydrolysis of the N-silylimines provides an efficient access to aromatic ketones [cf. (X)]. -(ORTIZ-MARCIALES, M.; TIRADO, L. M.; COLON, R.; UFRET, M. L.; FIGUEROA, R.; LEBRON, M.; DEJESUS, M.; MARTINEZ, J.; MALAVE, T.; Synth. Commun. 28 (1998) 21, 4067-4075; Dep. Chem., Univ. Puerto Rico, Humacao, PR 00791, P. R.; EN)