Purpose To report a case of unilateral acute idiopathic maculopathy (UAIM) associated with yellow fever. Observations A 59-year-old man presented with acute blurring of his vision 30 days after symptoms of yellow fever virus infection. Findings resembling unilateral acute idiopathic maculopathy of the left eye were noted on ophthalmoscopy, fluorescein angiography and optical coherence tomography. The right eye exam was normal. He was managed conservatively and recovered complete visual function in 8 weeks. Conclusions We describe a case of unilateral acute idiopathic maculopathy disease in a patient infected by yellow fever virus confirmed with reverse transcriptase polymerase chain reaction (RT-PCR).

Background: Many factors can influence the functional outcomes of macular hole surgery and some studies have tried to describe anatomical features that could predict successful treatment. The purpose of this study is to describe a new technique for evaluating the healing of macular holes after two surgical techniques using a black-and-white pixel binarization histogram software by optical coherence tomography angiography and its potential functional implications. Methods: This was a retrospective, observational case series of patients who presented with idiopathic full-thickness macular holes and underwent vitreoretinal surgery for successful macular hole closure using the internal limiting membrane peeling technique or the inverted peeling technique or the free internal limiting membrane flap technique. Optical coherence tomography angiography 3.0 × 3.0-mm scans were obtained postoperatively. The outer retina layer was analyzed separately; three different analyses were performed within a 3.0-mm-diameter area central circle, a 1.5-mm-diameter area, and a 0.5-mm-diameter area from the foveal center. The outer retinal layer images were evaluated by counting the number of black and white pixels. The inclusion criteria were patients with idiopathic macular holes who underwent ophthalmologic examinations and swept-source optical coherence tomography 1 week and 1 and 6 months postoperatively. The exclusion criteria were a traumatic macular hole or a history of eye trauma and a diagnosis of glaucoma or any other chronic ocular disease. The Mann-Whitney test was used to determine significance; P < 0.05 was considered significant. Results: Ten eyes of 10 patients who underwent vitreoretinal surgery to treat a macular hole either with the conventional peeling technique (n = 5) or the inverted/free internal limiting membrane flap technique (n = 5) were included. In the peeling group, the percentage of white pixels ranged from 7.22% to 18.40% in the 0.5 × 0.5-millimeter area in the macular center; the mean postoperative logarithm of the minimum angle of resolution best-corrected visual

Vogt-Koyanagi-Harada (VKH) disease is an inflammatory and autoimmune condition characterized by panuveitis, serous retinal detachments, and extraocular manifestations of the auditory, integumentary, and central nervous systems (CNS). Early diagnosis and prompt and adequate treatment with immuno-suppressive agents (corticosteroids and other immunosuppressive drugs) may halt disease progression and prevent recurrences and vision loss. The purpose of this article is to report a case of VKH.

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Antecedentes: A doença Vogt-Koyanagi-Harada (VKH) é uma condição inflamatória e auto-imune caracterizada por panuveite, descolamentos serosos da retina e manifestações extra-oculares do sistema auditivo, tegumentar e nervoso central. Os doentes com VKH podem ter bons resultados finais se tratados prontamente com agentes imunossupressores e assim evitar complicações. O objectivo deste artigo é relatar a evolução da fase da uveíte aguda da VKH.Relato de caso: Relatamos um caso de uma mulher de 58 anos de idade que se apresentou na sala de emer-gência de oftalmologia com uma história de 10 dias de dor de cabeça grave e uma acuidade visual progressivamente baixa no olho esquerdo (LE). Após sete dias ela desenvolveu uma baixa acuidade visual (VA) noutros olhos e um zumbido importante no ouvido esquerdo. O exame oftalmológico mostrou a acuidade visual melhor corrigida (BCVA) de 20/200 em ambos os olhos; os reflexos motores directos e consensuais diminuíram bilateralmente; reacção de câmara anterior com 2+ células em ambos os olhos. Na Fundoscopia: discos ópticos hiperemicos bilaterais, descolamento seroso da retina, dobras da retina no feixe papilomacular e nódulos de Dalen-Fuchs. A angiofluoresceinografia (AGF) mostrou hiperfluorescência macular bilateral (pinpoints). Tomografia de Coerência Óptica (OCT) mostrou fluido subretinal bilateral e perda de depressão foveal. Prednisona oral 1,2mg/kg/dia e dexametasona tópica foram introduzidas com afilamento progressivo durante 9 meses com melhoria completa da VA do olho direito e melhoria parcial da VA do olho esquerdo.Conclusão: A VKH pode causar perda de visão e cegueira. O diagnóstico precoce e o tratamento adequado com agentes imunossupressores podem travar a progressão da doença e prevenir as recidivas e a perda de visão.