The strategic significance of the output products defines advantage of innovative rocket-space industry activity. In order to implement such an activity innovation potential is needed. Its formation is carried out both on the basis of resource and strategic approaches. There appear difficulties connected with the specific aspects of rocket-space industry enterprises in the course of innovative activity determination. Permanent changes of external and internal conditions cause changes of goal-setting and requirements to innovative potential. The research reproduction of innovative potential as a criterion will allow defining current efficiency of rocket-space industry enterprises innovative activity.