Our results support the hypothesis that patients with epilepsy who die suddenly and unexpectedly have cardiac pathologic conditions that may be responsible for their deaths.

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Psychomotor retardation is a clinical hallmark of depression, but its functional basis is poorly understood This article presents an experimental method that attempts to differentiate between the cognitive and the motor components of behavior that might underlie psychomotor retardation These components are distinguished through systematic variation of cognitive and motor response demands in a series of reaction time tasks Depressed subjects are drug-free psychiatric inpatients diagnosed as either melancholic (endogenous subtype) or nonmelancholic (not endogenous) by Research Diagnostic Criteria with the Schedule for Affective Disorders and Schizophrenia. Results indicate a motor component to psychomotor retardation in both melancholic (n -12) and nonmelancholic (« = 14) groups relative to normal control subjects (n = 14). Melancholic patients manifest an additional, cognitive impairment that is not found in either the nonmelancholic or the control group A basic distinction between melancholic (or endogenous) and nonmelancholic (alternately termed nonendogenous, reactive, or neurotic) depression has received considerable research support over the last 20 years (Andreasen,

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