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Purpose The purpose of this study is to study the various adverse reactions caused post measles and rubella vaccination done during measles rubella (MR) vaccine campaign in India. Materials and Methods Prospective, observational study was done in a government tertiary care pediatric intensive care unit. Children aged between 9 months to 15 years, who presented with adverse effects (severe enough to warrant admission) within 7 days of MR vaccine administration. Results Most common presenting complaint was fever (44.8%), followed by vomiting (34.5%), abdominal pain and dizziness (31%). Abnormal body movements were noted in two children (6.8%) on first day and in one child on fifth day of vaccine administration. Two children (6.8%) presented with generalized macular rashes all over the body on 4th day after vaccination. Altered sensorium on same day of vaccine administration was the presenting symptom of one child. All children improved gradually and were discharged after few days with no mortality or long-term morbidity. Investigations were done according to the protocol of the unit; nothing came significant to be reported. Neither of the children had positive blood culture. Conclusion MR vaccination programs are scientifically sound, highly recommended and proven effective globally. Causality assessment of adverse events is still an evolving science, and despite taking all the measures and adopting all the available scientific methods, sometimes it is not possible to incontrovertibly prove the causal association of an event with a vaccine. Much more advancement in this area is needed.

Introduction: Hypertension among children and adolescents has increased significantly in the developed countries during the past two decades and similar trends are being observed even in the developing world. Methods: Mid adolescent boys and girls (14-16years) of three government and four private schools of Ujjain city were included with sample size of 1000. A pre designed questionnaire regarding nutritional and dietary history was prepared with measurement of anthropometry. Results: The overall prevalence of pre-hypertension and hypertension children in our study is 6.8% and 8.2% respectively, where as worldwide prevalence of hypertension is 7% to 19%. The prevalence of systolic pre-hypertension and systolic hypertension in children of government schools (14-16 yrs) was 7.5% and 8.5% respectively. In private schools out of 75 hypertensive students 49 (65.3%) (p=0.06) were consuming excess calorie. The incidence of systolic hypertension was low in the students with physical, activity ≥1hr/day and it was observed that both TV watching and Computer use were not associated with hypertension. Conclusion The prevalence of systolic hypertension in boys was higher in private schools as compared to government (7.8%>5.9%). Girls were more hypertensive in government as compared to private schools (12.4%>7.9%). Various factors which were found to have correlation with hypertension include calorie intake, number of meals per day, lack of physical activity in the present study.

Background: Thrombocytopenia is seen in various haematological and non haematological conditions and has been defined as platelet count less than 1.5 lakh/mm 3. Dysplastic changes are well known in Myelo-Dysplastic Syndrome (MDS) but these can be seen in other haematological conditions. Methods: This was a retrospective study done on 100 bone marrow aspirations in a tertiary care center in South India from Jan 2015 to Dec 2016. All bone marrow aspirations in this study period was retrieved and the slides were reviewed by two pathologists.