Scabies is one of the most prevalent infectious skin diseases in Indonesia, especially in boarding schools. Diagnosis of scabies can be made using the four cardinal signs through anamnesis and simple physical examination. The high incidence of scabies requires collaboration between various parties to diagnose and treat scabies. “DeSkab” (scabies detection form) is a form containing questions for non-medical personnel to detect scabies before being confirmed by trained medical personnel. Face and content validity of “DeSkab” is first established by boarding school’s supervisors, experts in community medicine, and dermatovenereologists. To establish reliability, study is conducted in Al-Hidayah Islamic Boarding School, Indonesia. Six non-medical personnel were chosen to examine 81 students of the boarding school using “DeSkab”. Each student is examined by three non-medical personnel, then confirmed through an examination by dermatovenereologists. Result of McNemar test shows that scabies detection by five nonmedical personnel have no statistically significant difference compared to the dermatovenereologist (McNemar test value of P>0.05). Based on this result, “DeSkab” proves to be an option for non-medical personnel to use as an instrument for detecting scabies in Indonesia.
Background Difficulty in diagnosing Chlamydia trachomatis infections, including chlamydial cervicitis, is a notable challenge in managing sexually transmitted infections in Indonesia. Gram staining is usually done to make a presumptive diagnosis despite its low sensitivity and specificity. Polymerase chain reaction (PCR) is considered the gold standard, but it is costly, technically demanding, and difficult to be performed in low-resource settings. Thus, rapid point-of-care tests with high sensitivity and specificity are needed to diagnose chlamydial cervicitis. Methods This cross-sectional study included symptomatic and asymptomatic high-risk women in the Mulya Jaya Sex Workers Rehabilitation Center in June to July 2020. Endocervical swabs from each participant were taken for QuickStripe™ chlamydia rapid test (CRT), Gram staining, and real-time PCR. Results A total of 41 participants were enrolled. The sensitivity and specificity for QuickStripe™ CRT were 73.6% (95% CI: 48.80%–90.85%) and 81.82% (95% CI: 59.72%–94.81%). Positive and negative predictive values were 77.78% (95% CI: 58.09%–89.84%) and 78.05% (95% CI: 62.39%–89.44%). Proportion of chlamydial cervicitis in study participants based on real-time PCR was 46.3%. Conclusions We concluded that QuickStripe™ CRT can be recommended as an alternative diagnostic test for high-risk populations in Jakarta.
Penegakkan diagnosis penyakit inflamasi kulit dilakukan berdasarkan anamnesis, gambaran morfologi, serta distribusi dari lesi. Namun, terkadang klinisi kesulitan untuk menyingkirkan diagnosis banding penyakit yang dialami oleh pasien. Dermoskopi merupakan alat diagnostik non-invasif yang dapat digunakan untuk membantu diagnosis kelainan kulit. Dermoskopi dapat membantu visualisasi struktur di bawah permukaan kulit hingga ke dermis superfisialis dan memperlihatkan morfologi lesi yang sulit teramati secara kasat mata. Pada awalnya dermoskopi dipakai sebagai pemeriksaan penunjang untuk tumor jinak dan tumor ganas kulit. Saat ini, dermoskopi digunakan secara luas dalam berbagai penyakit kulit antara lain penyakit infeksi dan infestasi kulit (entomodermoscopy), kelainan kuku dan lipat kuku (onychoscopy), kelainan rambut (trichoscopy), penyakit inflamasi kulit (inflammoscopy), serta membantu pengambilan keputusan dan evaluasi terapi. Pemeriksaan dermoskopi pada penyakit inflamasi kulit meliputi pengamatan morfologi dan distribusi pembuluh darah, warna dan distribusi skuama, gambaran folikuler, struktur lain, serta tanda spesifik yang dapat ditemukan pada penyakit tertentu. Dengan menggabungkan hasil anamnesis, pemeriksaan fisik, serta pemeriksaan dermoskopi, diagnosis penyakit inflamasi kulit menjadi lebih akurat.Kata kunci : dermoskopi, inflammoscopy, penyakit inflamasi kulit
Background: Melasma has been suspected to be linked with levels of thyroid hormone. There is no study that explains the association between thyroid hormone level with melasma severity. Objective: This study aims to find the discrepancies in the levels of thyroid hormone in varying severity of melasma by using two different measurement techniques. Methods: Subjects were chosen consecutively from the dermatology clinic at RSUPN Dr. Cipto Mangunkusomo hospital. Forty-eight patients participated in this study were categorized into mild melasma and moderate-severe melasma based on modified melasma area and severity index (mMASI) and Janus II measurement. Results: Statistically, mMASI measurement showed no significant association between varying melasma severity with levels of thyroid stimulating hormone and free T4 (FT4), P 0.375 and P 0.208, respectively. The Janus II examination using polarized light modality has a weak positive correlation with the serum FT4 level (r=0.3; P 0.039). Weak correlation was also found between the two measurement strategies, Janus II and mMASI (r= 0.314; P 0.03). Conclusion: There are no significant differences observed in levels of thyroid hormone between subjects with varying degrees of melasma severity.
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