Latar belakang. Usia 0-3 tahun merupakan golden age period yang tepat untuk perkembangan anak. Perkembangan anak meliputi kemampuan gerak motorik kasar, motorik halus, bahasa, dan personal sosial. Salah satu faktor yang sangat mempengaruhi perkembangan anak adalah pemberian stimulasi. Tujuan. Mengetahui hubungan stimulasi ibu dengan perkembangan anak usia 0-3 tahun di Kelurahan Penengahan Raya Kecamatan Kedaton Bandar Lampung.Metode. Desain penelitian ini kuantitatif observasional dengan pendekatan cross sectional dan teknik consecutive sampling. Data merupakan data primer dengan instrumen kuesioner yang sudah diuji validitas dan reliabilitasnya untuk menilai stimulasi ibu dan hasil skrining perkembangan dengan Denver II. Analisis data menggunakan uji chi-square.Hasil. Pada 80 responden, 44 (55%) ibu memberikan stimulasi motorik kasar baik dan 36(45%) kurang, 39(48,8%) ibu memberikan stimulasi motorik halus baik dan 41 (51,2%) kurang. 46 (57,5%) ibu memberikan stimulasi bahasa baik dan 34(42,5%) kurang. 33(41,2%) ibu memberikan stimulasi personal sosial baik dan 47(58,8%) kurang. Anak dengan perkembangan motorik kasar, motorik halus, bahasa dan personal sosial dalam kategori normal berturut-turut adalah 61 (76,2%), 61 (76,2%), 45 (56,2%) dan 68 (85%). Terdapat hubungan yang bermakna antara stimulasi ibu dengan perkembangan motorik kasar (p= 0,004), motorik halus (p=0,025), bahasa (p=0,000) dan personal sosial (p=0,001).Kesimpulan. Terdapat hubungan stimulasi ibu dengan perkembangan anak usia 0-3 tahun di Kelurahan Penengahan Raya Kecamatan Kedaton Bandar Lampung.

AIM:This study aimed to determine the effect of treadmill treatment on oxidative stress markers and endogenous antioxidant status seen from MDA, GSH, MnSOD enzyme specific activity and blood catalase of obese mice.MATERIALS AND METHODS:This research is experimental laboratory research using post-test control design group only. The study lasted for 28 days and was divided into 4 groups of study, i.e., group K (normal control), KP (obesity control), P1 (obesity mice with 1 x 10-minute treadmill treatment a day), and P2 (obesity mice with 2 x 10-minute treadmill treatment a day).RESULTS:The treadmill treatment had an effect on the improvement of the oxidative status of mice with a decrease of MDA level of obesity mice blood (p ≤ 0.05) compared to KP control. An elevated endogenous antioxidant status of obesity mice was seen from elevated GSH levels, MnSOD specific activity and blood catalase of obesity mice (p ≤ 0.05) compared with KP controls. Treatment of 1 x 10-minute treadmill per day decreased blood MDA level, increased GSH enzyme and increased specific activity of MnSOD enzyme and blood catalase of obese mice.CONCLUSIONS:The 2 x 10-minute daily treadmill did not differ significantly in improving the oxidative status and endogenous antioxidant status compared with the treadmill 1 x 10 minutes a day (p ≥ 0.05).

Background High-risk acute lymphoblastic leukemia (ALL) is one of the most common childhood malignancies in Indonesia. Many factors can inhibit the induction of remission. Hematological parameters are usually not normal. Identification of corresponding factors is important to increase the likelihood of successful inductions.Objective To assess for associations between hematological parameters and induction of remission in children with acute lymphoblastic leukemia.Methods Data were collected from medical records of ALL patients hospitalized in the Pediatric Ward at Dr. Kariadi Hospital from May 2014 – May 2016. Dependent variables were hemoglobin, leukocytes, platelets, and absolute neutrophil count (ANC) levels; the independent variable was induction of remission.Results Out of 55 patients, 33 (60%) had anemia, 6 (10.9%) had leukocytosis, and 1 (1.8%) had hyperleukocytosis, whereas 9 (34.5%) had leukopenia and 29 (52,7%) had normal leukocyte levels. Thirty-one subjects (56.4%) had thrombocytopenia, 15 (27.3%) had thrombocytosis, and only 9 (16.4%) patients had normal platelet counts. There were 29 (52.7%) with absolute ANC > 500, whereas 26 (47.3%) had ANC level ≤ 500. Most patients (80%) experienced remission induction, while 20% did not. There were significant associations between ANC level and induction of remission (P=0.010) as well as between platelet level and induction of remission (P= 0.033). Regression logistic test revealed that ANC level ≤ 500 was associated with a 7-fold lower remission event compared to ANC level > 500 (RR 7.147; 95%CI 1.38 to 37.14).Conclusion Lower ANC level (≤ 500) was significantly associated with lower remission compared to higher ANC level (> 500).

:     Background: Stunting is a condition of toddlers who have less length or height compared to age. Toddler stunting is a chronic nutritional problem caused by many factors, one of which is LBW. Babies born with LBW will be at high risk of morbidity, mortality, infectious diseases, underweight and stunting in the early neonatal period to childhood.The purpose of this study is to determine the association between  Low Birth Weight (LBW) with the incidence of stunting in toddlers (aged 24-59 months) in the Way Urang Community Health Center in South Lampung Regency.                         Method: This study uses an observational analytic method with a case control study design. LBW data is secondary data obtained by looking at the birth weight data of children under five listed in the Maternal and Child Health book Way Urang Community Health Center data. The statistical analysis uses the Chi Square test.                         Result: There is an association of Low Birth Weight (LBW) with the occurrence of stunting in toddlers (aged 24-59 months) in Way Urang Community Health Center South Lampung Regency. P value= 0,024.                         Conclusion: There is a significant association of Low Birth Weight with the incidence of stunting in toddlers (aged 24-59 months) in the Way Urang Community Health Center in South Lampung Regency.

Pendekatan intervensi managemen nutrisi menjadi salah satu program utama yang diharapkan mampu menurunkan kasus stunting di seluruh dunia khususnya Indonesia. Pengelolaan gizi ibu juga dapat dimulai sejak remaja karena status kesehatan seorang ibu didapatkan berkaitan dengan status gizinya di masa remaja. Sehingga peningkatan pemahaman dan perilaku remaja putri mengenai gizi seimbang khususnya dalam periode 1000 Hari Pertamaa Kehidupan (HPK) dapat mengoptimalkan penurunan kasus stunting. Model Pemberdayaan Masyarakat pada kelompok remaja putri melalui KOMSI ini dikembangan dengan tahapan pembentukan komunitas dengan kerjasama dengan pamong desa dan karang taruna Desa Negeri Katon, Pesawaran. Dilanjutkan dengan edukasi dan penyuluhan, edukasi dan focus group discussion untuk mengevaluasi pengetahuan, model KOMSI sekaligus menyusun formatur KOMSI. Hasil pretset edukasi dan penyuluhan menunjukkan 37% dengan nilai pengetahuan yang cukup dan 63% pengetahuan kurang dari 35 peserta remaja putri yang berusia antara 14 sampai 21 tahun. Hasil pengamatan post test, diketahui bahwa 11% peserta pengetahuan yanga masih kurang walau secara skoring terjadi peningkatan, 60% telah memiliki pengetahuan yang cukup dan 29% sangat baik. KOMSI dengan formatur ketua, sekeretaris, bendahara dan humas, melakukan koordinasi dengan pamong desa dan pamong Kecamatan Negeri Katon untuk mendapat arahan dan koordinasi bentuk kegiatan terkait kesehatan yang akan melibatkan KOMSI sebagai edukator kesehatan yang membantu berperan meningkatkan pengetahuan masyarakat khususnya di Kecamatan Negeri Katon, Pesawaran.