No abstract

There is no reference range for hepcidin. AE s.d. = standard deviation. IQR = interquartile range (1st quartile-3rd quartile). M = male values. F = female values.

The systemic effect of chronic periodontitis (CP) has been suggested by several studies as an etiologic factor and modulator of diseases based on the changes in the inflammatory marker levels. This study aimed to investigate the relationship between the changes in clinical periodontal outcomes and serum biomarkers (CRP, Il-6, albumin and percentage of leukocytes) after non-surgical periodontal therapy in systemically healthy adults. An interventional study was conducted with a sample of 29 individuals without CP (control group) and 33 with CP (CP group). Periodontal clinical variables were recorded, and the serum levels of inflammatory markers were measured. Statistical analysis included the chi-square and Student's t-tests and Pearson's correlation analysis. After 90 days of non-surgical periodontal treatment, a reduction of periodontal parameters and Il-6 in both groups could be observed (P < 0.001). the correlation analysis revealed a directly proportional correlation between changes in the probing depth (r = 0.349, P = 0.049) and clinical attachment level (r = 0.374, P = 0.034) with CRP in the CP group. The findings suggest a reduction of Il-6 serum concentration and periodontal clinical measures 90 days after periodontal therapy in both groups.

Although it is possible to obtain a reliable bond between enamel and composite resin, the ideal bonding method of composite resin to dentin still needs to be developed. Variables such as the type of adhesive system used and type of dentin substrate can influence on the adhesion. Objective: The purpose of this study was to compare the shear bond strength of composite resin restorations to human and bovine dentin using three adhesive systems. Material and methods: Fifteen human third molars sectioned into two halves and 30 bovine incisors were cut into blocks (4x4mm), embedded in acrylic resin and ground flat to expose the dentin. The specimens were randomly divided into six groups (n = 10): group 1 – human dentin using Scotchbond Multi-Purpose; group 2 – human dentin using Adper Single Bond 2; group 3 – human dentin using Adper Prompt L-Pop; group 4 – bovine dentin using Scotchbond Multi-Purpose; group 5 – bovine dentin using Adper Single Bond 2; group 6 – bovine dentin using Adper Prompt L-Pop. After composite resin restoration procedure, the specimens were stored into distilled water for 24h at 37ºC and then submitted to the shear test using a universal testing machine. The failure patterns were examined microscopically and classified as adhesive, cohesive in resin, cohesive in dentin or both, and mixed. The ANOVA (two-way) and Tukey’s post hoc were used. Chi-square test for independence was used for analysis of failure mode. The significance level was set at 5%. Results: A significant difference in shear bond strength was observed among adhesive systems (p = 0.031), with higher values for one-bottle adhesive (8.87±2.72) and lower for self-etching (6.38±3.15), and between the two types of substrate (p = 0.018), with higher values for human dentin. However, there was no significant difference for the adhesive system/substrate interaction (p = 0.11). Adhesive failure was the predominant failure mode for all adhesive systems and for the two substrates. Conclusion: Shear bond strength was different between human and bovine substrates and for the adhesive system used.

The aim of this study was to evaluate the shear bond strength of orthodontic resin and resin-modified glass ionomer cement on bonding of metal and ceramic brackets. Material and methods: Forty bovine teeth were sectioned and embedded into PVC with chemically-cured acrylic resin. The labial surfaces were flattened and received prophylaxis with pumice and water. Then they were divided into four groups, according to the bonding material and the type of bracket. Group 1: metallic bracket + Transbond XT; Group 2: metallic bracket + Vitremer; Group 3: ceramic bracket + Transbond XT; Group 4: ceramic bracket + Vitremer. The bonding was performed according to the manufacturers’ recommendations. The shear bond strength test was conducted in a universal testing machine (TIRAtest 2420) at a crosshead speed of 0.5 mm/min. Then, the fractured surfaces were evaluated using a stereomicroscope (x15 magnification) to check the adhesive remnant index. Data was subjected to two-way ANOVA and Tukey’s test for pairwise comparisons (α = 0.05). Results: The results suggested a non-significant effect of the interaction (p > 0.97), and only main factors were significant (p = 0.0001). The bond strength of Transbond XT was statistically higher than Vitremer. Ceramic brackets obtained the highest values of resistance when compared with metal brackets. Conclusion: The ceramic brackets bonded with Transbond XT orthodontic resin have excellent bond strength results.