Administering 50% GA prior to EMLA application enhances percutaneous absorption of EMLA, which accelerates the onset of adequate cutaneous analgesia, even without using an occlusive dressing.

Original ArticleNoegroho, et al. amounted to 303 cases. The cases consisted of 127 cases of fungal infection (42%) with a variety of cases of dermatophytosis, PVC, and candidiasis; 55 cases of bacterial infections (18%) with a variety of cases of impetigo, folliculitis, leprosy, ektima, erysipelas, furuncles, and abscesses; 40 cases of viral infections (13%) with variaty of cases of HFMD cases, Moluscum contagiosum, zooster, warts, varicella; and 81 cases of parasitic infections (27%) with a variety of cases of scabies, creeping eruption, and pediculosis capitis. Conclusion: Skin diseases caused by infections was still a dominant skin disease in the outpatient Dermatology clinic of RSUD Wonosari, with the number of cases 18.35% of all cases of skin and venereal diseases. The most common cause is infection by fungi (7.69%), followed by parasitic infections, scabies (4.91%), bacterial infections (3.33%), and viral infections (2.42%).

Background: Sebum production is associated with several factors including hormonal, and nutritional factors. Sleeping pattern could also affect changes in androgen levels associated with sebum production and acne. During Ramadan, moslems are obliged to fast from dawn to sunset, causing nutritional intake and sleeping pattern changes. Objectives: This study was aimed to find association between nutritional intake and sleeping pattern during Ramadan with sebum production. Methods: Ramadan fasting practitioners (40 male, mean age ±SD : 19.19±1.03 years) were evaluted before and 3 weeks into Ramadan fasting. Parameters assessed were nutrient intakes (using 24-hour food recalls), sleep quality and duration (using Pittsburgh Sleep Quality Index) and sleep diary. Sebum productions were measured using SebutapeR technique. Results: Significant decreases were found in protein (p=0.014), total fat (p=0.031), milkshake(p=0.001) and cheese intakes (p=0.013). Glycemic load was also decreased significantly (p=0.006). Despite no reduction in total sleep duration, night sleep duration was significantly reduced during Ramadan (p=0.000) associated with more subjects with poor sleep quality (p=0.039). Sebum production was increased significantly during Ramadan (p=0.028) Conclusion: Despite lower glycemic load and dairy products intakes, and lower sleep duration, Ramadan fasting was associated with increased sebum production. It was likely a result of circadian rhythm shift in sebaceous glands activities. Bangladesh Journal of Medical Science Vol.18(3) 2019 p.546-551

Psoriasis is a chronic inflammatory disease characterized by skin inflammation, epidermal hyperplasia, increased risk of arthritis, cardiovascular morbidity, and psychosocial challenges. Previous studies revealed the association of psoriasis with cardiometabolic diseases, in which dyslipidemia is a common feature. The objective of the study is to identify the correlation between lipid profile and disease severity in psoriasis patients. This study employed a cross-sectional design by using primary data from patients visiting the outpatient department of Dr Soedirman Kebumen District Hospital, Central Java. Disease severity was examined using Psoriasis Area and Severity Index (PASI) score. The levels of triglyceride, HDL-and LDL-cholesterol, and total cholesterol were measured from fasting blood plasma on the same day. Data were compared by utilizing one-way ANOVA or Kruskal-Wallis test as appropriate, and correlation between lipid levels and PASI score was analyzed by utilizing the Spearman correlation test. There were 33 psoriasis patients (20 male and 13 female) enrolled in this study; mean age was 43,6 ± 16,7 years old, and mean disease duration was 8,2 ± 9,5 years. Disease severity was mild in 19 (57,5%), moderate in 5 (15,2%), and severe in 9 (27,3%) patients, and mean PASI score was 12,8 ± 10,1. There were no significant differences of triglyceride levels (p = 0,700), HDL-cholesterol levels (p = 0,743), LDL-cholesterol levels (p = 0,840), and total cholesterol (p = 0,890) among groups of disease severity. There was no significant correlation between PASI score and triglyceride (r = 0,028; p = 0,879), HDL-cholesterol (r = −0,052; p = 0,775, LDL-cholesterol (r = −0,043; p = 0,812) and total cholesterol levels (r = −0,028; p = 0,875). However, there was a significant correlation between PASI score and disease duration (r = 0,423; p = 0,014). Meanwhile, there was no significant correlation between disease severity and lipid profile in psoriasis patients.