In the field of molecular analysis of cancer, there exists a need for a clinical device that can automate protocols for immunohistochemical and in situ hybridization diagnostic staining on tissue microarrays. The Tissue Microarray Antibody Spotter (TMAS) has been developed to provide fundamental improvements over current histological staining techniques by enabling precision application of reagents to individual biopsies within a tissue microarray. This allows for multiplexed reactions on a single slide and promises to significantly reduce costs associated with immunohistochemistry and in situ hybridization based assays. Additionally, because TMAS allows for testing of different biomarkers on each element of a tissue array, a complete cancer profile can be obtained from a single TMA slide. Ultimately this may lead to costeffective, faster and more accurate diagnosis of the patient.

No abstract

No abstract

A rigorous thermal monitoring regimen is considered standard practice by those responsible for maintaining critical electrical infrastructure. As thermal imaging technologies mature and infrared cameras become increasingly common, it becomes necessary to understand any limitations that may be imposed by methods that capture data infrequently. This paper will frame the benefits of implementing continuous, real time, thermal monitoring instead of performing infrequent scanning with hand-held infrared cameras, in an industrial process environment. Attention is focused on medium and low voltage switchgear due to the importance of their thermal behavior in these industrial settings. Specifically, continuous thermal sensing utilizing fiber-optic based sensors will be reviewed, along with installation considerations and methods for analyzing data.