Penuaan merupakan proses alamiah yang dilalui oleh setiap mahluk hidup bila mempunyai umur panjang, sekaligus sebagai proses yang sangat ditakuti oleh kebanyakan orang. Selama proses tersebut, terjadi perubahan anatomi dan penurunan fungsi organ tubuh. penerapan ilmu terkini dan teknologi-teknologi kedokteran untuk deteksi dini, pencegahan, pengobatan, dan pengembalian berbagai disfungsi yang berkaitan dengan usia dan penyakit. Tujuan penelitian ini adalah untuk mengetahui apakah pemberian ekstrak daun gandarusa (justicia gendarusa Burm .f) dapat mengurangi pembentukan kista fungsional dan mampu menghambat proses penuaan pada ovarium marmut. Rancangan penelitian ini adalah posttest only control group design, terdiri dari empat kelompok. Besar sampel 28 ekor marmut betina berusia 24 bulan, berat badan 600-650 gram. Pemilihan sampel secara random. Penelitian dilakukan selama 2 bulan dengan waktu perlakuan 28 hari. Kelompok kontrol diberikan 6 ml aquadest dan kelompok perlakuan masing – masing diberikan ekstrak daun gandarusa 6 ml peroral 2 kali sehari sesuai dosis. Sesudah perlakuan dilakukan pembedahan, pembuatan preparat histologi ovarium, dan pengamatan menggunakan mikroskop. Analisis data terdiri dari analisis deskriptif dan komparatif dengan bantuan komputer.Hasil penelitian menunjukkan peningkatan jumlah folikel skunder, dan mengurangi terbentuknya kista fungsional secara bermakna dengan nilai (p<0,05) pada kelompok perlakuan, disebabkan kemampuan ekstrak daun gandarusa sebagai fitoestrogen dan antioksidan alami menghambat terbentuknya radikal bebas, sehingga melindungi DNA dan sel dari kerusakan.Simpulan : ekstrak daun gandarusa meningkatkan jumlah folikel skunder, dan mengurangi terbentuknya jumlah kista fungsional. Saran: perlu penelitian lebih lama agar efek ekstrak daun gandarusa terhadap ovarium tampak lebih jelas.
The development of contraceptive methods is more focused on female contraception than men is still lacking. Papaya leaves are thought to have an antifertility effect due to the content of secondary metabolites, namely flavonoids, alkaloids, saponins, tannins and papain enzymes that have estrogenic effects that can disrupt hormone regulation in the hypothalamic-pituitary-gonadal axis. This study aimed to prove the administration of ethanol extract of papaya leaves (Carica papaya L.) on the histopathological features of the testicles of young adult mice (Mus musculus). Subjects and Method: This research uses an experimental study with a post-test only control group design. The samples used were male Swiss Webster strain mice (Mus musculus) 2-3 months old with a bodyweight of 20-30 grams as many as 36 individuals were divided into 2 groups. The control group (P0) was given 0.5 ml of Tween 3% and the treatment group (P1) was given ethanol extract of Papaya Leaf (Carica papaya L.) 0.21 mg/gram BW as much as 0.5 ml for 36 days orally. The data obtained were analyzed using the Independent Sample T-test. Result: A total of 11 articles from Asia continent (India, Bangladesh, Philipina, and Nepal).
Sexually transmitted infections (STIs) or venereal diseases are one of the reproductive health issues that are currently in the top 10 infectious diseases in several developing countries, such as in Indonesia. This type of infectious disease has a high risk in tourist areas due to its strong tendency for spreading the disease. This study aims to enhance the awareness and the understanding of the STI of traders in the tourist area, Nipah Beach, North Lombok Regency. The methods that are used counseling and education, and discussion. The result of the study shows after the implementation of this activity, the traders have a better understanding of STIs and they can apply reproductive health to individuals, families, and the tourist environment
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.