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The adolescent's reproductive health is the major problem that should take into consideration. To solve this problem, it needs an alternative strategy by using a media, reproductive health/kesehatan reproduksi (KEPO) game, in Android smartphone. The aim is analyzing the effect of KEPO game on the five dimensions of female adolescent's satisfaction. The research method was quasi-experiment, and the research design used pre-test post-test with control group design. The sampling technique used simple random sampling. The subject was 64 respondents of female student age of 12−15 years old in public junior high school in Bandung city. The respondents divided into two groups, the first one treated by KEPO game is 32 students of Public Junior High School 50 Bandung, while the control group was 32 students of Public Junior High School 8 Bandung, get counseling from Ujungberung Indah Public Health Center; the entire research conducted in April−May 2017. Research result shows the percentage differential of satisfaction average score improvement on both groups. The treatment group produces percentage of content 14.6%, display 23.6%, accuracy 11.4%, easiness 12.4%, and correctness 17%. In the other hand, control group produces content 5%, display 3%, accuracy 4.3%, easiness 2.8%, and correctness 4.7% with a p value for each indicator was p<0.05 on the intervention group and p<0.05 on the control one. Entirely, it known that adolescent's satisfaction from those five aspects in using KEPO game has a matter differential p<0.05, with satisfied percentage, was 84%. In conclusion, there was an effect of KEPO game on the five dimensions of female adolescent's satisfaction.

Background Preeclampsia increases maternal and perinatal mortality and is affected by calcium and magnesium levels. Reduced extracellular levels of calcium and magnesium constitute the pathogenesis of eclampsia. A reduction in the calcium-magnesium ratio may aid in the detection and prevention of preeclampsia. Material/Methods This was an analytical observational study with a cross-sectional design, including patients with and without preeclampsia (inpatient and outpatient). A total of 246 patients were included in this research; 138 patients had preeclampsia and 108 patients did not. All examinations of magnesium and calcium levels at the Hasan Sadikin Hospital Clinical Pathology laboratory were conducted using an ion selective electrode modified with methylthymol blue complexometric titration. Results Patients with preeclampsia had significantly higher average serum magnesium and calcium levels than did patients without preeclampsia (2.85 vs 2.09, P =0.0001; 4.45 vs 4.85, P =0.025, respectively). Patients with preeclampsia demonstrated significantly lower serum calcium-magnesium ratios than did patients without preeclampsia (1.98 vs 2.60, P =0.0001). Receiver operating characteristic curve analysis on the serum calcium-magnesium ratio showed an area under the curve of 68.0% ( P =0.0001), with a cutoff value of 2.36 (sensitivity 64.8%, specificity 62.3%), indicating that patients with serum calcium-magnesium ratios of <2.36 were predicted to have a risk of preeclampsia. Conclusions Patients with preeclampsia had significantly lower serum calcium-magnesium ratios than did patients without preeclampsia; therefore, a low calcium-magnesium ratio could be a risk factor for preeclampsia.

Objectives: To analyze the association between Ki-67 expression with the cyst size and stage of endometriosis, and the correlation strength between them. Methods: A cross-sectional analytic observational study involving 56 paraffin blocks from subjects diagnosed with endometriosis, who had undergone laparotomy or laparoscopic surgery. The study is conducted in Dr. Hasan Sadikin Hospital in September-November 2012. Results: Shows a significant association between Ki-67 expression and the size of endometriotic cyst (p < 0.0001), also with a strong correlation (r = 0.55) according to Guilford criteria. There is also a significant association between Ki-67 expression and the endometriosis stage (p < 0.0001), with a strong correlation (r = 0.564) according to Guilford criteria. Conclusion: Ki-67 expression is correlated with the cyst size and stage of endometriosis. [Indones J Obstet Gynecol 2013; 1-3: 124-8] Keywords: endometriosis stage, endometriotic cyst size, Ki-67

The problem of adolescent reproductive health has not been adequately addressed, although there have been many tried attempts both formally and informally. Adolescents aged 12-15 years old are suitable for early reproductive health education, so the needed media that suits their needs and developments. Reproductive health/kesehatan reproduksi (KEPO) game contains information about reproductive health and moral messages in the formation of self-concept, healthy reproduction, health motivation, and responsibility. The purpose of this study was for knowing the effect of using the KEPO game to the self-concept and motivation of adolescent reproductive health. The study layout uses a quasi-experiment with a pretest-posttest with control group design. The treatment group received a KEPO game, while the control group received the Young Health Programme (YHP). This study uses a sampling technique using simple random sampling with a sample of 42 students for each group. The analysis used is the nonparametric test. This research was implemented in the work area of the Public Health Center Ujungberung in Bandung city on the April-May 2017. The results showed that there was an effect of using the KEPO game to selfconcept and motivation of adolescent reproductive health (p<0.001). The increase in self-concept in the treatment group was 8.2%, while in the control group it was 2.2%. For reproductive health motivation, the treatment group experienced an increase of 9.5%, while the control group experienced an increase of only 0.8%. In conclusion, the KEPO game increased self-concept and reproductive health motivation in adolescents.