Red crystals of [H3O · (dibenzo‐18‐crown‐6)][Te2Br9] (1) were isolated from a solution of TeBr4 and dibenzo‐18‐crown‐6 in CH3CN containing a small amount of hydrobromic acid. The compound crystallizes in the triclinic space group P 1 with the cell dimensions a = 9.010(2), b = 13.403(3), c = 14.606(4) Å, α = 98.94(2)°, β = 100.40(2)°, and γ = 91.40(2)° (150 K). From a solution of TeCl4 in 1,4‐dioxane containing hydrochloric acid [H5O2][Te2Cl9] · 2 C4H8O2 (2) precipitates as colorless crystals in the orthorhombic space group Pnma with the cell dimensions a = 17.023(4), b = 13.389(4), and c = 10.900(3) Å (150 K). In both structures the [Te2X9]– anion (X = Cl, Br) consists of one TeX6 octahedron and one TeX5 square pyramidal unit connected by a common edge. In compound 1 the coordination sphere of the square pyramidal fragment is completed by a very weakly η6 bound benzo group of the cationic unit. In compound 2 an oxygen atom of the oxonium ion weakly interacts with the fivefold coordinated tellurium atom. The cationic units are a crown ether oxonium complex in 1 and a supramolecular 1,4‐dioxane‐oxonium network in 2.

Allogeneic stem cell transplantation (alloSCT) is a curative procedure for myelofibrosis. Elderly people are mainly affected, limiting the feasibility of myeloablative regimens. The introduction of reduced-intensity conditioning (RIC) made alloSCT feasible for older patients. Nevertheless, the incidence of myelofibrosis is not negligible in young patients, who are theoretically able to tolerate high-intensity therapy. Very few data are available about the efficacy of RIC-alloSCT in younger myelofibrosis patients. This study included 56 transplanted patients aged <55 years. Only 30% had a human leucocyte antigen (HLA)-matched sibling donor, the others were transplanted from a fully-matched (36%) or partially-matched (34%) unrelated donor. All transplants were conditioned according the European Society for Blood and Marrow Transplantation protocol: busulfan-fludarabine + antithymocyte globulin, followed by ciclosporin and mycophenolate. One patient experienced primary graft failure. Incidence of graft-versus-host disease grade II-IV was 44% (grade III/IV 23%). One-year non-relapse mortality was 7% and the 5-year cumulative incidence of relapse was 19%. After a median follow-up of 8Á6 years, the estimated 5-year progression-free survival and overall survival (OS) was 68% and 82%, respectively. Patients with fully-matched donor had a 5-year OS of 92%, in contrast to 68% for those with a mismatched donor (P = 0Á03). The most important outcomedetermining factor is donor HLA-matching. In conclusion, RIC-alloSCT ensures optimal engraftment and low relapse rate in younger myelofibrosis patients, enabling the possibility of cure in this group.

Gezielte Versuche zur Synthese neuer Halogenochalkogen(IV)‐Säuren führten mit Tellur und Brom zu den neuen Verbindungen [H3O(Benzo‐18‐Krone‐6)]2[Te2Br10] (1) und [H5O2(Dibenzo‐24‐Krone‐8)]2[Te2Br10] (2). Die [Te2Br10]2‐‐Anionen bestehen aus zwei kantenverknüpften verzerrten TeBr6‐Oktaedern, die Oxoniumkationen werden durch Kronenether stabilisiert. (1) kristallisiert in der monoklinen Raumgruppe P21/n mit a = 14, 520(5) Å, b = 22, 259(6) Å, c = 16, 053(5) Å, β = 97, 76(3)° und Z = 4, während für (2) die trikline Raumgruppe $P {\bar 1}$ mit a = 11, 005(4) Å, b = 12, 103(5) Å, c = 14, 951(6) Å, α = 71, 61(3)°, β = 69, 17(3)°, γ = 68, 40(3)° und Z = 1 gefunden wurde.

From solutions of TeBr4 in concentrated aqueous HBr red needles of the crystalline hexabromotellurous acid with the stoichiometric composition H2TeBr6 · 8H2O (1) were isolated (space group P21/n, a = 7.662(5), b = 9.796(6), c = 11.987(8) Å, β = 91.35(4)° at 259 Κ). If the HBr:TeBr4 concentration ratio in the system TeBr4/HBr/H2O was kept low, a novel acid with formal composition HTe3Br13 ·4 H2O (2) could be prepared (space group Cm, a = 13.501(5), b = 15.453(6), c = 9.153(3) Å, β = 138.11(2)° at 140 Κ). The X-ray structural analysis of 1 shows the acid to contain, besides regular octahedral [TeBr6]2- ions (Te-Br: 2.671(4)-2.716(4) Å), [Η9Ο4]+ hydroxonium ions (O ··· O: 2.48(3)-2.62(3) Å). The [H9O4]+ units are linked through a hydrogen bond system (O ··· O: 2.80(3)-2.97(4) Å) to form a three-dimen-sional network. The formula has to be written as [H9O4]2[TeBr6]. 2 is the first acid in this class with a trinuclear anion. Its structural formula is [H9O4][Te3Br13]. As a fragment of the Te4Br,6 cube the anion consists of three edge-sharing octahedra with a central triply bridging Br. The mean bond distances are 2.515 Å for terminal Te-Br, 2.944 Å for Te-μ2Br and 3.077 Å for Te—μ3Br. The Ο···Ο distances in the isolated [H9O4]+ hydroxonium ions are 2.45(3)-2.57(2) A. Raman spectra of both acids are reported.

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