Introduction. Periodontal tissue disease is one of the most common dental pathologies, which among young people occurs with a frequency of 60% to 99%. Therefore, the problem of finding new links in the pathogenesis, the reasons for the growing prevalence of periodontal disease, as well as effective methods for its early diagnosis and prevention, is relevant. Objectives. Establish the possibility of using individual stomatological and psychophysiological features to predict the development of periodontal disease. Materials and methods. 156 students aged 18-23 years old without systemic diseases were surveyed for some features of oral hygiene and nutrition. Also the study subjects underwent a dental examination, psychological testing and the assessment of individual typological features of higher nervous activity and autonomous regulation. The model for statistical prediction were designed using neural networks. Results. Two neural networks were designed with the best predictors among dental history and examination, psychological testing, parameters of higher nervous activity and heart rate variability analysis. The diagnostic sensitivity of the first prognostic model was 83.33 % and the specificity was 92.31 %. The second model was characterized by 90.00 % sensitivity and 78.57 % specificity. Conclusion. The method of modeling using neural networks based on the index assessment of the condition of teeth hard tissues, the level of oral hygiene and the evaluation of psychophysiological features can effectively predict the risk of periodontal disease development in young people

The aim: To establish criteria for individual thermal sensitivity in almost healthy individuals aged 17-20 years. Materials and methods: We surveyed 150 people aged 17-20 years. Heat sensitivity was previously assessed using our adapted questionnaire «Levels of heat sensitivity», in which according to the scale the number of points 0-6 indicates reduced heat sensitivity, 7-16 points - increased). All respondents underwent thermal testing. The subjects had auscultatory determination of pulse rate and blood pressure, after which the hands of both hands were immersed in a container with warm water (45° C) for 3 minutes. At the 2nd minute, pulse rate and blood pressure were determined. this procedure was repeated after the hands were removed from the water, and every 2 minutes until the pulse and blood pressure recovered over time. Before and after the heat test, a mathematical analysis of heart rate was performed using a computer software package, according to the manufacturer›s instructions. Results: After conducting a thermal test in people with hypersensitivity, an increase in the average values of heart rate and blood pressure. In the group of people with lower sensitivity to heat, heart rate and blood pressure after the heat test decreased or did not change. As a result of statistical processing of data from mathematical analysis of heart rate, it was found that in persons with hypersensitivity after the thermal test increased activity of the sympathetic nervous system, while in subjects with reduced sensitivity to heat showed a slight advantage of parasympathetic nervous system. Conclusions: Increased activity of the sympathetic nervous system in response to heat in people with hypersensitivity indicates the development of stress, and given the current trend towards long-term and constant increase in average annual temperature, this will lead to overstrain of regulatory mechanisms, depletion of functional reserves and reduced adaptability . Therefore, people with high heat sensitivity are particularly vulnerable to global climate change.

Eczema is a skin disease with a multifaceted clinical picture, numerous forms of manifestation and course and, last but not least, a life-modifying pathology that often requires lifestyle changes and reduces its quality. Identifying prognostic signs to predict the occurrence and severity of this disease is a priority for modern science. The purpose of the study is to build and analyze discriminant models of the possibility of occurrence and features of course of different forms of eczema in Ukrainian men of the first mature age depending on the characteristics of anthropometric parameters of the body. For men aged 22 to 35 years with true (n=34, including 16 mild and 18 severe) and microbial (n=38, including 28 mild and 10 severe) eczema, anthropometric examination according to the scheme of Bunak V.V. performed. Diagnosis of eczema was performed according to the nomenclature of ICD-10. The control group according to anthropometric data consisted of 82 practically healthy men of the same age, who were selected from the database of the research center of National Pirogov Memorial Medical University, Vinnytsya. Construction of discriminant models of the possibility of occurrence and features of the course of different forms of eczema depending on the anthropometric parameters of the body was carried out in the license package “Statistica 5.5”. It was found that the distribution of sick men on the truth of mild and severe eczema and microbial eczema of mild and severe course is possible only reliable interpretation of the obtained classification indicators between healthy and groups of patients (correct function in 76.0 % of cases, statistics Wilks’ Lambda = 0.074); when dividing sick men only into truth and microbial eczema – a reliable interpretation of the obtained classification indicators both between healthy and sick, and between sick truth and microbial eczema is possible (function is correct in 87.7 % of cases, Wilks’ Lambda statistics = 0.088); in the distribution of sick men only for mild or severe eczema – possible reliable interpretation of the obtained classification indicators between healthy and sick men, and between patients with mild or severe eczema only a slight tendency to interpret the obtained classification indicators (correct function in 84.4 % of cases, statistics Wilks’ Lambda = 0.088). In all cases, the constructed discriminant equations most often include the thickness of skin and fat folds (62.5 %, 57.1 % and 71.4 %, respectively) and body diameters (37.5 %, 42.9 % and 28.6 %, respectively). The obtained results confirm the prospects of using anthropometric research methods to predict the possibilities and features of eczema course and occurrence.

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Vadzyuk S. N., Shmata R. M. Features of autonomous regulation in young subjects with increased vestibular analyzer sensitivity. AbstractIntroduction: Each person's body have adaptation during the load due to different changes in the cardiovascular system. One of the first systems that responds to any factors and is actively involved in the processes of adaptation is the autonomic nervous system. It is known that as a result of excitement of the vestibular analyzer kinetosis develops -"motion sickness", which is accompanied by nausea, dizziness, unsteadiness of gait, general weakness. In this regard, assessment of the functional state of the body and its adaptive reserves continues to be one of the most important problems of modern physiology and medicine.The purpose of the study was to evaluate the features of autonomous regulation in subjects with increased sensitivity of the vestibular analyzer.Materials and methods: 60 people between the ages of 18-19 were examined. Vestibular sensitivity was determined with a help of questionnaire. The state of the autonomic nervous system was determined by analyzing heart rate variability using a 5-minute ECG registration technique. The registration and recording was performed by the «PolySpectr +» computer program.Results and discussion: Based on the questionnaire, the students were divided into 2 groups: with proper and with increased vestibular sensitivity. In students with proper vestibular sensitivity, the LF / HF ratio of 1.06 indicates a balanced type of autonomic heart rate modulation. The analysis of spectral indices in subjects with increased vestibular sensitivity 12 showed a lower overall power of the spectrum, which indicates less functional reserves of the organism. We set much higher HF waves, which indicates an increase in the activity of the parasympathetic system. This is also indicated by the LF / HF ratio of 0.59. When considering the rhythmograms of subjects with increased vestibular sensitivity, 64% of 1-st grade rhythmograms, 20% of 2-nd grade rhythmograms and 16.6% of 3-rd grade rhythmograms were registered. When assessing rhythmograms of the 3-rd class, it can be concluded that the level of functional reserves of subjects with increased sensitivity of the vestibular analyzer can be reduced, which may lead to a decrease in the adaptive capacity of these subjects. Conclusions:In subjects with increased vestibular sensitivity, the parasympathetic autonomic nervous system makes the greatest contribution to the regulation of cardiac rhythm.Key words: increased sensitivity of the vestibular analyzer, autonomous regulation, functional reserves of the organism, rhythmograms.