Journal homepage: http://www.ijcmas.com Urinary Tract Infections (UTIs) commonly occurs in pregnancy, due to the morphological and physiological changes that take place in the genitourinary tract.Asymptomatic bacteriuria refers to the presence of bacteria in urine, and is a condition in which urine culture reveals a significant growth of pathogens that is greater than 10 5 bacteria/ml, but without the patient showing symptoms (Gilbert et al., 2005). The apparent reduction in immunity of pregnant women appears to encourage the growth of both commensal and non-commensal microorganisms (Scott et al., 1990). The most untoward consequence of Asymptomatic bacteriuria in pregnancy is severe renal damage. Asymptomatic bacteriuria in some woman may lead to pyelonephritis or cystitis during pregnancy, while in others there may be no symptoms of urinary tract infection through-out gestation, but may develop urinary tract infection during puerperium. Pregnancy enhances the progression from asymptomatic to symptomatic bacteriuria which could lead to pyelonephritis and adverse obstetric outcomes such as prematurity, low birth weight (Connolly and Thorp, 1999) and higher fetal mortality rates (Nicolle, 1994;Delzell and Leferre, 2000). This study therefore was carried out to determine the prevalence of Asymptomatic bacteriuria (ASB) in pregnant women and to isolate, identify the causative organisms; and to test the antimicrobial susceptibility of isolated pathogens. A total of 200 pregnant women who came for ante-natal checkup in outpatient department at Govt. Maternity Hospital, Nayapool. Hyderabad were studied over a period of one year. Clean catch midstream urine sample was collected into a sterile container and then subjected to culture method. Out of 200 patients studied, significant bacteriuria was noted in 36 (18%) cases and 8(4%) patients had insignificant bacteriuria. Highest incidence of 22 cases (61.11%) were reported in the age group of 26-35 years. It was found that Asymptomatic bacteriuria showed significant increase with respect to parity, higher incidence was seen in multi gravidae 58.9% (3 and 4th parity). Incidence of Asymptomatic bacteriuria was found to decrease with the increase in gestation time, maximum number were noted in first trimester 19 (52.78%) followed next by second trimester 13 (36.11%) and in third trimester 4 (11.11%). E. coli 20 (55.56%),was the most common etiological agent followed by Klebsiella spp in 9 cases (25%) Coagulase negative Staphylococcus in 2 cases (5.56%) and Pseudomonas spp in 2 cases (5.56%), Proteus mirabilis and Enterobacter, Staphylococcus aureus each in one case (2.78%) all the strains were sensitive to imipenem and meropenem. As asymptomatic bacteriuria is associated with complications in pregnancy, it is therefore imperative that pregnant women be screened for bacteriuria, periodically in every trimester of the gestational period. Routine urine culture tests should be carried out for all antenatal women to detect asymptomatic bacteriuria, and every positive case should ...

Cardiac disease complicates about 1% of pregnancies. It is a major cause of maternal morbidity & mortality. AIM: To study clinical profiles of pregnant women with cardiac diseases and the maternal and fetal outcome cases. METHODOLOGY: It is a retrospective study for a period of 18 months from October 2012 -March 2014 conducted at Vanivilas hospital attached to Bangalore Medical College. 80 women with cardiac disease were included, and their associated co-morbid conditions, mode of delivery and follow-up up to 5 days were noted. Maternal complications like heart failure, pulmonary edema, cardiac arrest, ICU admissions, and death were noted. Fetal outcomes were studied in terms of apgar score, presence of congenital heart disease, SGA, NICU admissions, death etc., RESULTS: 87.5% of the patients were booked elsewhere. Only 8.75% of them were in the NYHA class 3 or 4. 67.5% patients had RHD. There were no maternal deaths, only 7.5% required ICU care. 42.5% had prior cardiac surgeries. About 93% had vaginal deliveries which were assisted by forceps in only 42.5% cases. There were 7.5% NICU admissions with perinatal mortality of 5% and the mean birth weight was 2.23kg. CONCLUSION: Heart disease in pregnancy is a high risk condition has a major impact on pregnancy. Early diagnosis by proper antenatal care and interventions could be the key to the prevention of complications.