Introduction: Abnormal uterine bleeding (AUB) is one of the commonest gynaecological problems. Etiology of AUB may be structural and functional and varies according to age group. Histological pattern of endometrial sampling along with clinical and radiological findings remains the diagnostic standard for clinical diagnosis of endometrial pathology which ultimately helps in deciding the management of the patients. Objectives: To determine histopathological pattern of endometrial biopsies in patients with AUB attending Birat Medical College Teaching Hospital. To determine the pattern of menstrual abnormality in patients with AUB in different age groups. Methodology: We conducted a prospective hospital based cross sectional study for a period of one year (1 April 2019 to March 31 2020). Histopathological findings of all endometrial biopsy samples in patients with AUB were examined. Patients were categorized into different age groups and the patterns of menstrual abnormality were also documented. Results: 166 patients presenting with AUB underwent endometrial biopsy. Most of them were of perimenopausal age group (42.77%). Menorrhagia was the most common presenting menstrual abnormality. Histopathological examination predominantly revealed normal cyclical endometrium. Hyperplasia was seen more frequently in patients > 40 years of age. Malignancy was diagnosed in 2.41%, all were adenocarcinoma and was seen in > 50 years age. Conclusion: AUB is a common gynaeco-pathological problem with varied clinical presentation and multiple causes. Functional endometrial changes account for the highest histological pattern. However hyperplasia and malignancy are important cause of AUB in perimenopausal and post menopausal age group's women.

Introduction Breast lump constitute significant proportion of surgical cases. It is necessary to distinguish between benign and malignant lesions for definite treatment. Fine needle aspiration cytology (FNAC) is widely adopted for the pathologic assessment because of its accuracy and ease of use.Objective The present study was done to find out the frequency of various patterns of breast lesion on FNAC and the common age - group in which the lesions occurs.Methodology This is a four years retrospective study carried out from December 2011 to January 2016. The 553 patients who presented with palpable breast lump, and have underwent FNAC irrespective of age and sex were included in the study. All the datas were collected from the patients record form. FNAC findings were correlated with the data from histopathology records to determine the sensitivity and specificity of FNAC.Results The majority of the patients were female and majority of lump was benign. Fibroadenoma was the most common lesion accounting for 32.18 % of all lesions and most commonly occurring in age group between 21 -30 years. Fibrocystic disease was second common benign lesion accounting for 30.56 also commonly accounting in the age group 21- 30 years. Carcinoma breast was seen in 5.42 % of cases (30/553) occurring most commonly in the female patients above 30 years of age. Most common age group for gynaecomastia in male breast was 11 – 20 years.Conclusion FNAC is a rapid and safe method for diagnosing palpable breast lump into benign and malignant categorizes and thus avoiding unnecessary surgery.Birat Journal of Health Sciences 2016 1(1): 27-32

A digital fibromyxoma is a rare soft tissue tumor, which occurs in the finger and toes around the subungual and periungual region. Histopathologically, it consists of a well-circumscribed unencapsulated dermal tumor composed of spindle and stellate cells in a loose fascicular pattern embedded in a myxocollagenous stroma. We report this rare case of superficial acral fibromyxoma presenting as an asymptomatic subungual mass in the greater toe in a middle age female.