No abstract

Late premature infants are those who were born at GA of 34 to 36 weeks. Despite the GA, the high weight and growth rates, this group of newborns is much more likely than full-term children to experience disruptions in neonatal adaptation, damage to the respiratory system, CNS, the development of infectious complications, asphyxia, hypothermia, hypoglycemia, hyperbilirubinemia. All of these lead to an increase in morbidity, mortality and disability not only in the first months of life, but also in the future, therefore late premature infants cannot be treated as/kind of “almost full-term.” This bibliographical review represents the data on the features of the development of various pathological processes, outcomes and treatment options in late preterm infants.

The article presents data about maternal and prenatal influences lead to «programming» of arterial hypertension (AH) in the child's later life. A special group that is threatened by the development of AH at an older age is premature children and children with intrauterine development delay due to a small number of nephrons and the launch of prenatal programming of hypertension. The state of the mother's health before conception, as well as the use of assisted reproductive technologies, despite a normal pregnancy in general and the birth of a healthy newborn can provoke the development of hypertension in childhood.

No abstract

Convulsions in full-term and especially in premature newborns are observable pathologies. Selection of anticonvulsant therapy is very difficult: newborns have particular pharmacokinetics of drugs, insufficient data on doses and therapeutic concentrations of anticonvulsants in the blood (premature infants mainly). This article is an overview, with an emphasis on the features of dosing and pharmacokinetics of anticonvulsants in term and preterm infants.