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This study summarizes up-to-date information about the biopositive effects of low radiation treatment (LRT), radiation hormesis, and our experimental devices. In addition, we present a favorable treatment result in a patient with advanced rectal carcinoma who received LRT at home using a radon gas aspirator. The patient was a 61-year-old man who underwent proctectomy in 2010. During the additional first-line chemotherapy, apparent increases in tumor makers identified multiple remote metastases in the lung, sacrum and liver. Sacrum pain limited his activity of daily living and impeded his coming to our facility for LRT. Then, we decided to provide him home LRT using a radon gas aspirator. He inhaled radon gas for 15 minutes at least 3 times a day at home, resulting in remarkably reduced tumor markers and sacrum pain relief. He could walk, keep sitting up without support and sleep in the spine position again after receiving home LRT. No influence of radon gas inhalation on the second-line chemotherapy was observed. The favorable effects of LRT lead us to believe that the newly-developed devices will provide the clinical significance on malignant diseases. To establish the LRT regimen, further clinical investigation and data accumulation are thus called for.

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Ion association constants of two types of poly(vinylamine) and poly(ethylenimine) were determined from pH measurements of the polyamine/counter ion mixtures at an aqueous solution of the polymers (5 × 10−4 equiv mol dm−3). The results are discussed in terms of chemical structure (distance between reacting groups, and straight or branched chain), molecular weight, and ionic strength. The ion association at very low concentration protonated polyamines was promoted by the close location of amino groups. When the bound counter ions became close to each other, further ion association was inhibited by counter ions which had already bounded. From the colloidal titration of these polyamines, the stoichiometry could be discussed, especially under the conditions where all amino groups on the polymer are converted into ammonium ions. The results of the colloidal titration indicated that the stability constant for the ion association was drastically increasing near the equivalence point of the colloidal titration.