Symptomatic intracranial atherosclerotic disease (sICAD) remains a challenging disorder in the neurovascular field. Despite best medical treatment, the recurrence rate for stroke remains high in patients with intracranial high-grade stenosis (>70–99%). Furthermore, two large randomized trials (SAMMPRIS and VISSIT) failed to prove the efficacy of percutaneous transluminal angioplasty and stenting in patients with sICAD. Drug-coated balloon percutaneous transluminal angioplasty (DCB-PTA) represents an alternative treatment modality with therapeutic benefits for interventional cardiology. However, there are very few articles in the existing literature that relate to the use of DCB-PTA in sICAD patients. Here, we aimed to review the rationale underlying the use of DCB-PTA in sICAD patients and summarize recent developments in the neurovascular field.

BACKGROUND On displaced scaphoid fractures treated with prolonged cast immobilisation may result in temporary joint stiffness and muscle weakness in addition to a delay in return to sports or work. Fixation of scaphoid fractures with a percutaneous screw has resulted in a shorter time to union and to return to work or sports. The purpose of this study was to evaluate the results of percutaneous screw fixation scaphoid fractures with respect to time to radiographic union and to return to work. MATERIALS AND METHODS In 18 patients with fracture of the scaphoid, fixation with a percutaneous screw was done. Time to fracture union, wrist motion, grip strength and return to work as well as overall patient satisfaction at the time of a two-year follow-up were evaluated. RESULTS Of the 18 patients in the study, mean radiological fracture union time was 10 weeks (range 8-15 weeks). Wrist function was excellent in 10 cases, good in remaining 5 cases and poor in 3 cases. The mean DASH score in all patients at the end of one year was 23.16. Patients had returned to work after an average of 1 month. CONCLUSION Percutaneous screw fixation of scaphoid fractures resulted in faster radiographic union and return to function. The specific indications for and the risks and benefits of percutaneous screw fixation of such fractures must be determined in larger randomised prospective studies.

Introduction: Osteoarthritis of knee is more common among all types of arthritic conditions. High tibial osteotomy is an accepted surgical technique for treatment of medial compartment arthrosis of knee in younger patients. Selection of the appropriate patients, extensive pre-operative planning and accurate surgical technique are essential for successful outcome. The methods of high tibial osteotomy include open wedge osteotomy and closed wedge osteotomy, the later procedure being more popular. Aims and Objectives: To assess the functional outcome among patients undergoing high tibial osteotomy. Methodology: A hospital based prospective interventional study was done on 30 patients of osteoarthritis with varus deformity. For all the 30 patients after a proper preoperative assessment the surgical intervention in the form of high tibial osteotomy was done and the outcome was evaluated using knee society scoring system. Results: Among the study population 73.3% of the patients had grade III type of osteoarthritis and only 26.6% had grade IV type of osteoarthritis based on Kellgren and Lawrence type of classification. The mean knee score and the mean functional score of the patients before surgery were 54.6 and 53.9 respectively and post operatively at the end of 12 months the knee score and functional score was 83.1 and 82 respectively. A statistically significant improvement was seen in both the knee society score and the functional score. Conclusion:The main improvements seen in this study was the increase in the knee score and functional score after high tibial osteotomy for the patients of osteoarthritis with varus deformity. Appropriate patient selection, proper osteotomy types and precise surgical techniques are essential for the success of high tibial osteotomy.