Background & Objectives
Adherence to the Mediterranean diet (MedDiet) has been reported to be associated with a lower risk of various chronic diseases. This cross‐sectional study aimed to investigate the potential association between adherence to the MedDiet and periodontitis, which is highly prevalent in young Moroccan individuals.
Methods
We evaluated 1075 Moroccan individuals (72% women, mean [standard deviation] age = 20.2 [1.5] years). Adherence to the MedDiet was assessed using the MedDiet score (MDS) based on the frequency of intake of eight food groups (vegetables, legumes, fruits, cereals or potatoes, fish, red meat, dairy products, and olive oil). A value of 0 (unhealthy) or 1 (healthy) was assigned to each food group, and the MDS (range, 0‐8 points) was generated by adding the individual scores, with a higher score indicating better adherence to the MedDiet. The logistic regression model was used to evaluate the MDS (high [5‐8 points]/low [0‐4 points]) and each component score (1/0) with the presence of periodontitis, which was determined through full‐mouth periodontal examinations. Age, sex, and oral health behavior were considered as potential confounders.
Results
In total, 693 (64.5%) study participants showed high MDSs. Periodontitis was observed in 71 (6.6%) participants. No significant association between MDS and periodontitis was observed. Nonetheless, olive oil consumption, a component of the MDS, showed a significant inverse association with periodontitis (adjusted odds ratio = 0.55; 95% confidence interval, 0.32‐0.96).
Conclusions
The MedDiet was not significantly associated with periodontitis among young Moroccans. However, frequent consumption of olive oil may have a protective effect against periodontitis, although the temporal association needs to be clarified in further studies.
Aggressive periodontitis (AgP) is a form of periodontitis that affects adolescents and has a significantly higher prevalence in individuals of African descent. AgP typically shows familial aggregation, suggesting a genetic predisposition. Young age, good health status, rapid attachment loss, and familial aggregation are the primary features of this disease. AgP has been closely linked to specific bacterial strains of
Aggregatibacter actinomycetemcomitans
.
A. actinomycetemcomitans
strains isolated from patients with AgP produce leukotoxin (LtxA), which specifically affects polymorphonuclear leukocytes in primates, especially humans. High-throughput 16S rRNA gene sequencing and bioinformatics analyses revealed differences in the subgingival microbiota between patients with AgP and those with chronic periodontitis (ChP). The genera
Atopobium
and
Prevotella
show increased prevalences in AgP than in ChP. According to AgP susceptibility, several single nucleotide polymorphisms have been detected in different genes in individuals of African descent. Interleukin (IL)-1α and IL-1β genetic polymorphisms may be associated with the severity of both ChP and AgP. An elevated serum level of IL-17 produced by Th17 cells may be a characteristic of AgP. Analyses of the relationships among bacteria, host defenses, genetic predisposition, and numerous other factors are required to understand the progression of this disease.
When activated the platelets release growth factors that play an essential role in bone healing such as Plateletderived Growth Factor, Transforming Growth Factor-β, Vascular Endothelial Growth Factor and others. Several techniques for platelet concentrates such Platelet Rich Plasma (PRP) and Platelet Rich Fibrin (PRF) have been introduced in surgical field for the prevention of hemorrhage and acceleration of tissue regeneration. Recently, a novel technique of fabricating growth factors-enriched bone graft matrix have been proposed termed as "sticky bone" or "mineralized plasmatic matrix", which contains platelets and fibrin concentrate in a liquid state; these materials can become bound to bone particles. The filling material is easy to shape and a PRF-type membrane is also generated. In our case report, mineralized platelet matrix have been used after the extraction of a fractured single rooted tooth in order to preserve the dimensions of the post-extractive socket, facilitate new bone formation and to reduce healing time.
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