Serum NSE, GRIA 1, and S100B were increased with mercury exposure. GRIA 1 and S100B levels were observed to have the power to discriminate neurological symptom positive and negative groups. The increase in S100B levels are thought to be protecting the neurons and preventing further NSE elevations.
The detection of high S100B levels in peripheral circulation after acute ischemic stroke and the correlations of S100B levels with infarct size (good) and disability (poor) imply that S100B protein may be used as a peripheral marker in acute ischemic stroke patients.
ÖZETGenç yaş serebrovasküler hastalıkların sebepleri arasında vertebral arter diseksiyonu son yıllarda daha sık bildirilmektedir. Spontan olabileceği gibi boyun manipulasyonlarını veya travmayı takiben de ortaya çıkabilir. Olguların 3'ü kadın (ortalama yaş: 35±265 yıl), 7'si erkek (ortalama yaş: 37.71±4.96 yıl) idi. İki olguda boyun bölgesine uygulanan travma öyküsü vardı. Nörolojik muayenede tüm olgularda serebellar bulgular ön planda idi. Radyolojik incelemelerde 2 olguda bilateral, 5 olguda sağ ve 3 olguda sol vertebral artere ait vasküler değişiklikler izlendi. Hastaların tümüne antikoagülan tedavi verildi. Dokuz olguda tam iyilik hali görülürken bir olgu sekel olarak iyileşti. Vertebral arter diseksiyonunda hızlı tanı ve uygun tedavi ile prognoz genellikle iyidir. Dijital substraksiyon arteriografi disseksiyon tanısında altın standarttır. Bu yazıda vertebral arter diseksiyonunda klinik ve radyolojik özellikler gözden geçirildi. Anahtar Sözcükler: İnme, vertebral arter, diseksiyon.
CLINICAL AND RADIOLOGICAL EVALUATION IN VERTEBRAL ARTERY DISSECTIONS
ABSTRACTIn recent years, vertebral artery dissection (VAD) is reported more frequently as a cause of young cerebrovascular accidents. It can occur spontaneously or following a neck manipulation and trauma. The patients were 3 females (mean age: 35±26 years) and 7 males (mean age: 37.71±4.96 years). Only 2 patients described neck trauma. Cerebellar findings were prominent in all cases. On radiological investigation, vascular changes of vertebral arteries were detected bilaterally in 2 cases, right in 5 and left in 3 cases. All the cases were treated with anticoagulant therapy and cured but 1 with sequela. Prognosis of vertebral artery dissection is generally good by early diagnosis and treatment. In this article, we reported clinical and radiological properties of 10 vertebral artery dissection cases.
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