This paper discusses methods for reducing beam hardening effects and metal artefacts using spectral x-ray information in biomaterial samples. A small-animal spectral scanner was operated in the 15 to 80 keV x-ray energy range for this study. We use the photon-processing features of a CdTe-Medipix3RX ASIC in charge summing mode to reduce beam hardening and associated artefacts. We present spectral data collected for metal alloy samples, its analysis using algebraic 3D reconstruction software and volume visualisation using a custom volume rendering software. The cupping effect and streak artefacts are quantified in the spectral datasets. The results show reduction in beam hardening effects and metal artefacts in the narrow high energy range acquired using the spectroscopic detector. A post-reconstruction comparison between CdTe-Medipix3RX and Si-Medipix3.1 is discussed. The raw data and processed data are made available (http://hdl.handle.net/10092/8851) for testing with other software routines.

Restoration of critical sized defects of the mandible still poses a major problem in the field of Oral and Maxillofacial Surgery. The current gold standard of treatment relies on the use of autologous grafts and therefore, has associated disadvantages such as donor site morbidity and insufficient bone for prosthetic rehabilitation. Recent advances in the fields of bone tissue engineering and distraction osteogenesis provide an alternative treatment modality to restore the aforementioned critical sized defects. These alternative modalities offer patients and clinicians multiple advantages such as decreased morbidity and increased volume of bone for prosthetic restoration. The aim of this review was to evaluate the bone regeneration capacity of bone tissue engineering and distraction osteogenesis in preclinical in vivo animal models against the current gold standard.

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Purpose Additive manufacturing (AM) has the potential to revolutionise the fabrication of complex surgical instruments. However, AM parts typically have a higher surface roughness compared to machined or fine cast parts. High surface roughness has important implications for surgical instruments, particularly in terms of cleanliness and aesthetic considerations. In this study, bulk surface finishing methods are described to produce end-use selective laser melting parts. Design/methodology/approach The aim was to achieve a surface finish as close as possible to machined parts (Ra = 0.9 µm, Wa = 0.2 µm, Pv = 7.3 µm). A sample coupon was designed to systematically evaluate different finishing techniques. Processes included bulk finishing, blasting and centrifugal finishing methods on individual parts, as well as heat treatment before and after surface finishing. Findings Abrasive blasting or centrifugal finishing alone was not adequate to achieve an end-use surface finish. White oxide vapour blasting at high water pressure was the most effective of the abrasive blasting processes. For centrifugal finishing, a 4 h runtime resulted in an acceptable reduction in surface roughness (Ra = 2.9 µm, Wa = 2.0 µm, Pv = 34.6 µm: inclined surface [30°]) while not significantly increasing part radii. The combination of finishing methods resulting in the smoothest surfaces was white oxide blasting followed by 4 h of centrifugal finishing and a final glass bead blast (Ra = 0.6 µm, Wa = 0.9 µm, Pv = 6.9 µm: inclined surface [30°]). The order of these methods was important because white oxide blasting was significantly less effective when applied after the centrifugal finishing. Originality/value Collectively, these results describe the development of a practical bulk finishing method for stainless steel surgical instruments produced by AM.

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