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BACKGROUND It is a known fact that giving the blood helps the other in more than one way. One pint of blood given by the donor can save the lives of as many as three individuals. The aim of the study was to estimate the effect of lipid profile after 7 th , 30 th and 90 th days of blood donation. MATERIALS AND METHODS This is a descriptive study. 30 healthy volunteers were included in the study without any major illness. Total cholesterol was estimated by CHOD-POD method. HDLc was estimated by phosphotungstic acid method. TG was estimated by GPO-POD method. LDLc was estimated by using formula of Friedewald et al. RESULTS All the parameters of lipid profile, e.g. TC, LDL, VLDL except HDL was highly significantly decreased (p < 0.001) after 7 th and the effects continued till 30 th day after blood donation, which was highly significantly decreased (p < 0.05, HDL). It was significantly increased (p < 0.05) after 7 th and 30 th day of blood donation. At 90 th day, all values were normalised. CONCLUSION The act of blood donation has favourable hypolipidaemic effect even in normal healthy volunteers, which starts as early as 7 days and gets normalised by 90 days with continued raised levels of HDL.

Aims: This study aimed to analyze the effect of different investment techniques and pattern materials on the surface roughness of raw castings from nickel-chromium alloy. Settings and Design: This is an experimental in vitro study carried out in Bharati Vidyapeeth Dental College and Hospital, Sangli, Maharastra. Materials and Methods: Sixty square-shaped wax patterns, measuring 10 mm × 10 mm × 2 mm, were divided into four groups. A phosphate-bonded investment material (Bellasun, Bego, Germany) was used to invest 15 samples of inlay wax and kept under normal atmospheric pressure and the remaining 15 wax patterns were invested under a pressure of 3 bars for 30 min, and then allowed to bench set for another 30 min. The same investing techniques were carried out for the remaining thirty samples made from pattern resin. Statistical Analysis Used: The surface roughness (μm) of the castings was measured by a profilometer. Student's “unpaired t -test” was used for the statistical analysis. Results: Specimens that were invested at atmospheric pressure had significantly more surface roughness (μm) values than those invested under increased pressure ( P < 0.01). Conclusions: Wax patterns exhibited the least surface roughness when invested under pressure and can be recommended as the material and technique of choice. In addition, resin patterns invested under increased pressure produced smoother casting surface than those invested at atmospheric pressure, and the difference is highly significant.

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