Background. Oral mucositis is the chief complication of head and neck chemotherapy. This study was conducted to evaluate Hypozalix artificial saliva and propolis mouthwash efficacy for the prevention of chemotherapy-induced oral mucositis in leukemic patients.Methods. The present double-blind clinical trial was carried out on 72 patients undergoing chemotherapy. The patients were assigned to 3 groups. In the control group, CHX mouthwash and fluconazole were used by the subjects. In groups 1 and 2, Hypozalix and propolis mouthwashes were added to the combination therapy used in the control group. The results were compared between the three groups after 14 days.Results. Mean score A was significantly higher than mean score B in children (P = 0.001). In contrast, mean score A was significantly lower than mean score B in young adults (P = 0.003).Conclusion. Use of Hypozalix spray or propolis mouthwash in association with CHX mouthwash and fluconazole simultaneously at the start of chemotherapy resulted in a decrease in chemotherapy complications after 14 days. In many cases the use of propolis mouthwash yielded better results and the patients exhibited a greater tendency to continue to use it.

Background: Considering the high success rate of osseointegration, there is ever-increasing use of dental implants. The mechanisms and biologic response of peri-implant tissues are different depending on the biocompatibility of the implant material. The aim of this study was to compare the proinflammatory cytokine levels in the gingival crevicular fluid (GCF) around dental implants with ceramic and titanium abutments. Materials and methods:All the patients with dental implants referring to two private offices of two prosthodontists from June to August 2016 were examined in relation to implant health, and eligible subjects, based on inclusion criteria, were included in this study with a slit-mouth design. In this context, on one side titanium implants and, on the other side, ceramic implants were used. Samples were collected from the peri-implant sulcus in each patient and sent to the immunology laboratory for determination of interleukin (IL)-6 and IL-1β proinflammatory cytokine levels using an enzyme-linked immunosorbent assay kit. Data were analyzed with Statistical Package for the Social Sciences version 16. Statistical significance was set at p < 0.05. Results:The results showed lower levels of IL-1β and IL-6 in the GCF around ceramic abutments compared with titanium implants. In addition, statistical comparison between IL-6 and IL-1β levels showed higher levels of IL-6 around titanium and ceramic abutments compared with IL-1β levels. Comparison of Proinflammatory Cytokine Levels in Conclusion:Based on the results of this study, the human body immune response to ceramic abutments is much better than that to titanium implants.Clinical significance: Considering that proinflammatory cytokine levels in GCF around ceramic abutments are lower than titanium ones, ceramic abutments are preferred for clinical usage.

Introduction: Despite a decrease in the number of adult edentulous individuals, the number of individuals who lose all their teeth and need complete dentures is on the increase. One of the most important principles of fabrication of complete dentures is to achieve patient satisfaction. In the present cross-sectional study, the gradual trend of patients' satisfaction with complete dentures was evaluated. Materials and methods: In a descriptive study with pre-and post-test design, carried out in 2013 on 30 patients referring to the Department of Prosthodontics, Tabriz Faulty of Dentistry, the patients' gradual satisfaction with complete dentures was evaluated one week and 2 months after delivery of dentures in 7 aspects, including masticatory efficacy, satisfaction with mastication of soft and hard foods, ease of cleaning of dentures, perception of food tastes, articulation and overall satisfaction. A researcher-made questionnaire was used, whose validity and reliability had been confirmed. The questionnaire determined the patients' satisfaction by a value ranging from zero to 10. Repeated-measures ANOVA was used to analyze data. Results: Thirty subjects were included in the present study. Changes in patients' satisfaction from the first week to the second month were significant in terms of mastication of soft and hard food items, ease of cleaning the dentures, articulation and overall satisfaction (P=0.022, P=0.023, P=0.018, P=0.001 and P=0.001, respectively). Changes in patients' satisfaction with masticatory efficacy and perception of food tastes from the first week to the second month were not statistically significant (P=0.092 and P=0.144). Conclusion: In the present study, patients' satisfaction increased in all the aspects. Although such increase in satisfaction with mastication of soft and hard foods, ease of cleaning the dentures, articulation and overall satisfaction was statistically significant, it was not significant in relation to perception of food tastes and masticatory efficacy.

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Objective: To evaluate the effect of repeated removal and placement of abutments during prosthetic stages on increasing proinflammatory cytokine levels around dental implants. Material and Methods: All the patients with dental implants, referring to the prosthodontics private office during a 3-month period, were examined in relation to the health of the implants and included in the present study based on inclusion criteria; the patients had a multi-unit abutment on one side of the jaw and a conventional healing abutment on the implant on the other side of the jaw. Samples of gingival crevicular fluid were taken from all the eligible subjects for immunological analyses. The samples were taken from the sulcus around each implant in each subject. The samples were sent to the immunology laboratory for determination of IL-6 and IL-1β proinflammatory cytokines with the use of an ELISA kit. Data were analyzed with SPSS 16 and Descriptive statistics and T-test was used. Statistical significance was set at p<0.05. Results: The results showed that the mean concentrations of IL-1β and IL-6 in the group with multi-unit abutment were less than those in the conventional abutment group. In addition, comparison of the means of IL-6 and IL-1β concentrations showed that in both groups the concentration of IL-6 was higher than that of IL-1β. Conclusion: The use of multi-unit abutments resulted in less inflammation compared to the use of conventional two-segment abutments, which require repeated removal and placement during the prosthetic stage.