In laparoscopic cholecystectomies, lidocaine infusion had superiorities over esmolol infusions regarding the suppression of responses to tracheal extubation and postoperative need for additional analgesic agents in the long run, while esmolol was more advantageous with respect to rapid recovery from anesthesia, attenuation of early postoperative pain, and modified Aldrete recovery (MAR) scores and time to reach MAR score of 9 points.

SUMMARY A disease consisting of persistent muscle cramps involving distal muscle groups that occurred in 12 members of the same family is described. The cramps appeared on exertion and in full relaxation or during sleep. In the third generation they appeared in the second decade; in the fourth and fifth generations in childhood with higher frequency and intensity of cramps. The disease is not sex linked and seems to be dominantly inherited. Electromyography showed no myotonic response on insertion. Motor unit potentials were normal. Continual waxing and waning electrical discharges corresponding to clinically visible contractions of parts of the muscles were present. Repetitive nerve stimulation caused no change in the amplitude of evoked muscle potentials. On spinal anaesthesia or nerve block the muscle contractions continued but became painless. The movements were only stopped with local infiltration of anaesthetic into the muscle. There were no cramps on ischaemic work. Drug studies revealed no benefit on carbamazepine, slight relief with meprobamate, and complete disappearance with potassium chloride. The remission outlasted the treatment for three months and then cramps of milder degree reappeared. Repeated potassium chloride treatment was not effective. The cramps increased on hydrochlorothiazide, and 12 hours after spinal anaesthesia. In the authors' opinion the disease should be considered as not belonging to any known nosological entity.We have observed a disease appearing in many cated that the disease is of a type previously unsiblings of a family and in all of them with the known.

In laparoscopic cholecystectomies, lidocaine infusion had superiorities over esmolol infusions regarding the suppression of responses to tracheal extubation and postoperative need for additional analgesic agents in the long run, while esmolol was more advantageous with respect to rapid recovery from anesthesia, attenuation of early postoperative pain, and modified Aldrete recovery (MAR) scores and time to reach MAR score of 9 points.

Objective Staphylococcus are the leading agent of treatment difficulties in both community-acquired and hospital-acquired infections. The formation of methicillin resistance has made the use of glycopeptide antibiotics compulsory in the treatment. Glycopeptide antibiotics have been widely used in methicillin-resistant Staphylococcal infections, but the rapid and accurate identification of the susceptibility of these antibiotics is of great importance, since the susceptibility of intermediate susceptible and resistant strains to glycopeptides has begun to be known in recent years.Materials and Methods In our study, susceptibilities of vancomycin and teicoplanin in 100 Staphylococcus aureus and 100 coagulase negative Staphylococcus strains isolated from various clinical samples sent to Kahramanmaras Sutcu Imam University Medical Faculty Hospital Medical Microbiology Laboratory were investigated by VITEK-2 (BioMeriéux, France) automated system and E-test method. The sensitivities of antibiotics were evaluated according to CLSI criteria.Results All strains were found sensitive to vancomycin and teicoplanin by e-test method. According to the automated system, all strains were susceptible to vancomycin, whereas one MRSA strain was resistant, one MRCNS strain was intermediate susceptible, and seven MSCNS were intermediate susceptible.Conclusion According to our study, glycopeptide antibiotics can still be safely used in the treatment of methicillin-resistant Staphylococcus. However, the use of these antibiotics should be cautious because of the reporting of indermetidate susceptible and resistant strains. For this reason, it is of great importance to determine the most appropriate methods for accurate and rapid determination of glycopeptide antibiotic susceptibility. ( Sakarya Med J 2017, 7(2):92-96 )