This study evaluated the inhibitory potential of ethyl acetate extract of Parmotrema tinctorum (PTEE), an edible lichen, against aldose reductase (AR) and carbohydrate digestive enzymes such as α-glucosidase and α-amylase. It was also screened for antioxidant activities by using DPPH, ABTS, superoxide and hydroxyl radical-scavenging assays. PTEE exhibited α-glucosidase, α-amylase and AR inhibition along with significant antiglycation potential with an estimated IC50 value of 58.45 ± 1.24, 587.74 ± 3.27, 139.28 ± 2.6 and 285.78 ± 1.287 μg/mL, respectively. Antioxidant activity of PTEE against DPPH (IC50 396.83 ± 2.98 μg/mL), ABTS (151.34 ± 1.79 μg/mL), superoxide (30.29 ± 1.17 μg/mL) and hydroxyl (35.42 ± 1.22 μg/mL) radicals suggests the antioxidant potential of P. tinctorum. Significant antioxidant activity and inhibitory potential against carbohydrate digestive enzymes and AR suggest that P. tinctorum can be developed as functional food/nutraceuticals for diabetes after detailed study.
<em>Cassia auriculata</em> L. (CAL) popularly identified as Tanner’s Cassia and <em>Cassia fistula</em> L. (CFL) is generally known as Golden Shower. Both plants belong to the Family, Fabaceae. These plants are used in skin disease, as hepatoprotective, as anticancer agent and as antioxidant agent. The intention of current article is to put forward the comparative pharmacognostical analysis of <em>Cassia auriculata</em> and <em>Cassia fistula</em> roots in terms of macroscopic evaluation, microscopic evaluation, physicochemical evaluation, extractive values and phytochemical analysis. Thin Layer Chromatography study was carried out for CAL and CFL and data pertaining to the above cited evaluations were recorded for both, CAL and CFL roots. The present study may help in differentiating among these species and these pharmacognostic parameters may serve as a tool for identification, authentication and standardization of CAL and CFL.
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