ObjectivesSystemic immune‐inflammation index (SII) is a novel, inflammatory biomarker whose role in predicting several chronic systemic diseases has been recently identified. However, its association with generalized stage III grade C periodontitis in young adults remains unknown.Material and MethodsThe study is a multicentered, double‐blind, hospital‐based case–control clinical study. Periodontal examination comprised of recording plaque index, sites with bleeding on probing, pocket depth and clinical attachment loss for patients with generalized stage III grade C periodontitis and periodontally healthy group. Complete blood counts were obtained and used for calculating SII, neutrophil‐lymphocyte ratio (NLR) and platelet‐lymphocyte ratio. Collected data were then subjected to statistical analyses.ResultsSII was significantly higher in patients with generalized stage III grade C periodontitis compared to periodontally healthy individuals (723.87 vs. 537.74 × 109/L, p < 0.0001). SII is associated with severe periodontitis in young adults (odds ratio [OR]:11.86, 95% CI 9.61–20.76, p < 0.0001) after adjusting for factors found significant in univariate analysis. Receiver operative curve analysis demonstrated a fair predictive validity of SII in detecting generalized stage III grade C periodontitis in young adults (AUC: 0.766, 95%CI 0.731–0.799, p < 0.0001, sensitivity 81.27%, specificity 76.50% and diagnostic accuracy 78.89%). SII did not exhibit superior predictive validity when compared with NLR in the context of generalized stage III grade C periodontitis (AUC for SII: 0.766, 95%CI 0.731–0.799, AUC for NLR: 0.788, 95% CI 0.754–0.819; p = 0.28).ConclusionSII is associated with generalized stage III grade C periodontitis in young adults.

Background: The concept on minimally invasive surgical technique (MIST) is rapidly evolving in the field of medicine and Dentistry. MIST in periodontics is beneficial in enhancing clinical performance and in terms of patient-related factors also. Aims: The aim of this study was to assess the knowledge and practice behaviors about MIST in periodontics among dental students, dental practitioners, and academicians. Materials and Methods: An online questionnaire was prepared as Google Form and was distributed to respondents to assess their knowledge and practice behaviors about MIST. Statistical Analysis Used: A descriptive analysis comprising counts and the percentage was performed for all the variables. Categorical variables were compared among the different groups using the Chi-square test. Results: The study revealed that most of the respondents had adequate knowledge of MIST but only 46% of them had performed MIST procedures in daily clinical practice. Conclusions: There is sufficient knowledge about MIST and its implications in periodontics among dental students and professionals. However, there is a need to emphasize the clinical applications and more training to enhance skills and practice about MIST.

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