This work describes a bio-potential acquisition system for portable ubiquitous healthcare applications using flexible polydimethylsiloxane dry electrodes (FPDEs) and a low-power recording circuit. This novel FPDE used Au as the skin contact layer, which was made using a CO2 laser and replica method technology. The FPDE was revised from a commercial bio-potential electrode with a conductive snap using dry electrodes rather than wet electrodes that proposed reliable and robust attachment for the purpose of measurement, and attaching velcro made it wearable on the forearm for bio-potential applications. Furthermore, this study proposes a recording device to store bio-potential signal data and provides portability and low-power consumption for the proposed acquisition system. To acquire differential bio-potentials, such as electrocardiogram (ECG) signals, the proposed recording device includes a low-power front-end acquisition chip fabricated using a complementary metal-oxide-semiconductor (CMOS) process, a commercial microcontroller (MSP430F149), and a secure digital (SD) card for portable healthcare applications. The proposed system can obtain ECG signals efficiently and are comfortable to the skin. The power consumption of the system is about 85 mW for continuous working over a 3 day period with two AA batteries. It can also be used as a compact Holter ECG system.

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This paper presents a portable low-power battery-driven bioelectrochemical signal acquisition system for urea detection. The proposed design has several advantages, including high performance, low cost, low-power consumption, and high portability. A LT1789-1 low-supply-voltage instrumentation amplifier (IA) was used to measure and amplify the open-circuit potential (OCP) between the working and reference electrodes. An MSP430 micro-controller was programmed to process and transduce the signals to the custom-developed software by ZigBee RF module in wireless mode and UART in able mode. The immobilized urease sensor was prepared by embedding urease into the polymer (aniline-co-o-phenylenediamine) polymeric matrix and then coating/depositing it onto a MEMS-fabricated Au working electrode. The linear correlation established between the urea concentration and the potentiometric change is in the urea concentrations range of 3.16 × 10−4 to 3.16 × 10−2 M with a sensitivity of 31.12 mV/log [M] and a precision of 0.995 (R2 = 0.995). This portable device not only detects urea concentrations, but can also operate continuously with a 3.7 V rechargeab-le lithium-ion battery (500 mA·h) for at least four days. Accordingly, its use is feasible and even promising for home-care applications.

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Abstract:This study presents a self-testing platform with a foreground digital calibration technique for successive approximation register (SAR) analog-to-digital converters (ADCs). A high-accuracy digital-to-analog converter (DAC) with digital control is used for the proposed self-testing platform to generate the sinusoidal test signal. This signal is then implemented using an Arduino board, and the clock signal is generated to test the ADCs. In addition, fast Fourier transform and recursive discrete Fourier transform (RDFT) processors are adopted for dynamic performance evaluation and calibration of the ADCs. The third harmonic distortion caused by the non-linearity of the track-and-hold circuit, the mismatch of the DAC capacitor array, and the direct current (DC) offset of the comparator can be calculated using the processors to improve the ADC performance. The advantages of the proposed platform include its low cost, high integration, and no need for an extra analogy compensation circuit to deal with calibration. In this work a 12 bit SAR ADC and an RDFT processor are used in the Taiwan Semiconductor Manufacturing Co., Ltd. (TSMC) 0.18 µm standard complementary metal-oxide-semiconductor (CMOS) process with a sampling rate of 18.75 kS/s to validate the proposed method. The measurement results show that the signal-to-noise and distortion ratio is 55.07 dB before calibration and 61.35 dB after calibration.