The most challenging diseases such as obesity and diabetes are growing wider and its treatment is a major challenge for healthcare professionals. Most of these metabolic diseases are because of the impact of lifestyle on health. Many studies have recognized a high intake of fruits, greens and other vegetables, nuts and pulses play an important role in our daily diet. Biological constituents are important to combat such diseases and can act as nutritional supplements for treatment of diabetes, cancer, obesity and cardiovascular diseases. The aim of this article is to explore the role of all these exotic fruits and vegetable food in the pathophysiology of metabolic diseases and in alteration of diabetes and obesity.

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HPTLC method which is simple, particular and robust has been developed for the simultaneous estimation of Catechin and Curcumin from an Ayurvedic formulation. The method was validated using parameters such as linearity, specificity, and precision, limit of quantification (LOQ), limit of detection (LOD), accuracy and robustness as per ICH guidelines. The present work deals with development of HPTLC method for simultaneous estimation of catechin and curcumin in marketed Ayurvedic formulations. Chromatographic separation of the drugs was performed on Merck TLC aluminium plates pre-coated with silica gel 60F254 as the stationary phase. The mobile phase selected was toluene:ethyl acetate: formic acid (7: 2.5: 0.5 v/v/v). The sample solutions were prepared in methanol and linear ascending development was carried out in twin trough glass chamber and scanned at 269 nm using Camag TLC scanner. The two markers were resolved successfully with Rf values 0.23±0.02 and 0.58±0.02 for catechin and curcumin, respectively. The regression analysis data indicated good linear relationship for the calibration plots for Catechin and Curcumin in the range of 1900-2500 ng/spot and 200-800 ng/spot and regression coefficient was 0.990 and 0.997 respectively. The proposed method can be used for the estimation of these markers in combined Ayurvedic formulation.

Objective: The present research has been undertaken for the formulation and evaluation of Benzoyl Peroxide Injection. It is used for Antiacne activity. Methods: Benzoyl peroxide is used as Antiacne. Methyl paraben, Propyl paraben and benzalkoniumchloride were used as preservatives. Water for injection is used as a vehicle. The following parameters were evaluated such as clarity test, leakage test, chearity test, assay and Sterility test. Results: The clearity test shows clear solution. Drug chearity test shows no chear in the vials. Leakage test shows no leakage in the vials. pH and drug content show the F1 batch was better the other batches. IR confirmed that all functional groups are same as benzoyl Peroxide. Conclusion: It was concluded that F1 batch is the good than the other batches. So F1 batch is good for the Parenteral use.