Atopic dermatitis (AD) is a common chronic inflammatory skin condition characterized by intense pruritus and a waxing and waning course. AD often presents in infancy and childhood and can persist throughout adulthood. The exact cause of AD is unknown, but it likely reflects an interplay between genetic and environmental factors. AD affects up to 20% of children in the United States, and prevalence may be increasing. Treatment can be effective in alleviating symptoms but serves only to manage the disease, not cure it. Appropriate therapy can also prevent significant complications, such as infection, sleep disturbance, behavioral problems, and growth impairment.

No abstract

We present a special case of an 8-year-old girl diagnosed with severe drug reaction with eosinophilia and systemic symptoms due to trimethoprim-sulfamethoxazole for urinary tract infection prophylaxis for congenital vesicoureteral reflux. The patient is believed to have developed drug reaction with eosinophilia and systemic symptoms because of her underlying renal disease.

No abstract

Basal cell nevus syndrome (BCNS) is a rare autosomal dominant condition best known for the development of early and multiple basal cell carcinomas (BCCs). Because the condition requires lifetime surveillance for new cancers, an efficient method of identification and treatment is desirable, especially in children. Dermoscopy and carbon dioxide laser have previously been shown to be effective in the identification and treatment, respectively, of BCCs in BCNS. We present here a case illustrating that the use of these modalities in a single session provides patients with safe and effective treatment that is efficient, cosmetically acceptable, and minimally disruptive to their lives.