A Cu-catalyzed asymmetric alkynylation of cyclic N-sulfonyl ketimines was developed, providing the corresponding chiral α-tertiary amines with up to 98% ee. The method tolerates some variations in cyclic N-sulfonyl ketimine and alkyne scope. These products could be used in several transformations, in particular, the products of 6-membered cyclic N-sulfonyl ketimines could be easily converted to linear chiral α-tertiary amines. This asymmetric alkynylation provides an efficient, gram-scale, low-cost transition-metal catalyzed synthesis of chiral α-tetrasubstituted propargylamines.

A one-pot method for the synthesis of six novel 1,2,4-triazole-3-selones in excellent yields at room temperature has been achieved via reaction between potassium selenocyanate and an aroyl chloride followed by the addition of isonicotinohydrazide.

A simple, one-pot synthesis of six 1-aryl-2,4,10a-triazaphenanthrene-3-selones has been achieved with moderate to good yields via a three-component condensation of isoquinolin-1-amine, potassium selenocyanate and variously substituted benzoyl chlorides in acetone at room temperature.

A one-pot method for the synthesis of six novel 5-aryl-1,3-dimethyl-7-selenoxopyrimidino[4,5- d]pyrimidine-2,4(1 H,3 H)-diones in excellent yields at room temperature has been achieved via reaction between potassium selenocyanate and an aroyl chloride followed by the addition of 6-amino- N,N′-dimethyluracil.

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