Indonesian people know and are used to using the cat's whiskers plant (Orthosiphon stamineus B.) in medicine. The part of the plant that is commonly used by the community is the leaf. Cat whiskers leaves contain flavonoid compounds where these compounds have antioxidant activity that can counteract free radicals. The purpose of this study was to determine the total flavonoid content and antioxidant activity contained in the cat whiskers leaf extract. The sample in this study was cat whiskers leaves obtained from Makassar, South Sulawesi. Then extracted with 96% ethanol solvent by maceration method. Testing the total flavonoid content as querstin using 2% AlCl3 reagent and potassium acetate and testing antioxidant activity using the DPPH method. The results obtained showed that the total flavonoid content calculated as quercetin in the leaf extract of the cat's whiskers (O. stamineus B.) was 7.34158 mg QE/g or 0.734158% and the antioxidant activity of the cat's whiskers leaf extract expressed as IC50 of 65. ,62513 ppm and is included in the group of strong antioxidants.
Tanaman Kecombrang memiliki kandungan kimia seperti alkaloid, flavonoid, polifenol,steroid, saponin, dan minyak atsiri. Kandungan senyawa fitokimia pada tanaman diketahui mempunyai peranan yang sangat penting bagi kesehatan termasuk fungsinya dalam pencegahan terhadap penyakit. Tujuan dari penelitian ini adalah untuk menentukan nilai MIC (Minimum Inhibitory Concentration) dan MKC (Minimum Killing Concentration) dari Ekstrak Daun Kecombrang (Etlingera elatior) terhadap pertumbuhan Candida albicans dengan metode dilusi cair. Penelitian ini merupakan eksperimen murni menggunakan ekstrak daun kecombrang lalu ditentukan nilai MIC dan MKC dengan menggunakan metode dilusi cair. Konsentrasi yang digunakan adalah 1,25 %; 2,5%; 3,75%; 5%; 6,25%; 7,5%; 8,75%; 10%; 12,5%; 15%; 17,5%; 20%; 22,5%; 25% b/v. Hasil penelitian menunjukkan bahwa nilai MIC (Minimum Inhibitory Concentration) ekstrak Daun Kecombrang terdapat pada konsentrasi 6,25% b/v dan nilai MKC (Minimum Killing Concentration) terdapat pada konsentrasi 8,75% b/v. Hal ini menunjukkan bahwa ekstrak Daun Kecombrang (Etlingera elatior) efektif untuk menghambat dan membunuh jamur Candida albicans.
Tanaman Kecombrang memiliki kandungan kimia seperti alkaloid, flavonoid, polifenol,steroid, saponin, dan minyak atsiri, dimana kandungan kimia tersebut dapat berperan dalam pencegahan penyakit. Tujuan dari penelitian ini adalah untuk menentukan potensi antimikroba hasil fraksinasi ekstrak daun kecombrang terhadap Candida albicans penyebab keputihan pada ibu hamil. Penelitian ini merupakan eksperimen murni menggunakan ekstrak daun kecombrang, diisolasi menggunakan kromatografi kolom sehingga diperoleh fraksi-fraksi. Hasil fraksinasi selanjutnya diuji potensi antimikrobanya terhadap Candida albicans penyebab keputihan pada ibu hamil. Zona hambat yang diperoleh diukur untuk menentukan potensi antimikroba hasil fraksinasi ekstrak Daun Kecombrang tersebut. Hasil penelitian Daun Kecombrang (Etlingera elatior), dapat disimpulkan bahwa isolasi senyawa kimia ekstrak etanol Daun Kecombrang (Etlingera elatior) diperoleh 3 senyawa murni. Ketiga senyawa murni tersebut dapat menghambat Candida albicans, rata-rata diameter zona hambat dari senyawa A = 13,66 mm, senyawa C = 10,40 mm dan senyawa E = 9,33 mm. Hasil statistik one way anava menunjukkan bahwa fraksi A (F.A) memiliki potensi antimikroba yang berbeda dengan fraksi C (F.C) dan Fraksi E (F.E) (sig p < 0,05) sedangkan fraksi C (F.C) dan Fraksi E (F.E) memiliki potensi antimikroba yang sama (sig p > 0,05).
Etlingera elatior contains chemical compounds that prevent and treat leucorrhoea. However, they are used conventionally, and therefore, they are less effective and efficient. The purpose of this study was to formulate the liquid soap extract of Kecombrang Leaf (Etlingera elatior) and determine the stability of its physical quality and activity as an anti-vaginal discharge. The study uses dried simplicia of Kecombrang leaves extracted by the maceration method with ethanol 96%. It was formulated into liquid soap with a concentration variation of 6.25% and 8.75%. Each formula was evaluated for physical quality, microorganism contamination, and activity tests before and after the storage are accelerated. The results obtained by Etlingera Folium extract could be formulated into liquid soap with a concentration of 6.25% and 8.75%. The stability test results are accelerated, and each concentration meets the requirements of the organoleptic, foam resistance, and pH tests. Microorganism contamination test results also meet the needs of SNI & BPOM and have anti-vaginal discharge activity. The liquid soap preparation of 8.75% has an activity greater than the concentration of 6.25%.
Research has been conducted on the treatment of phlegm cough with miana leaf extract in vitro (effective dose of miana leaf extract as an expectorant and antibacterial agent causing cough with phlegm). The study aims to compare the antioxidant activity of miana leaves from 3 locations where it grows, determine the types of contaminant bacteria in the sputum of cough sufferers, determine the minimum value of inhibitor concentration (MIC) and MKC of miana leaves against the test bacteria causing cough with phlegm, determine the effective dose of miana leaves that can used as a reference for coughing up phlegm and proving the potential of miana leaves as a sputum thinner. Miana leaf extraction is done by the juicer method. Antioxidant activity testing uses the DPPH method. Determination of test bacteria is done by isolating and identifying contaminant bacteria in the sputum sample of cough with phlegm. Testing the effectiveness of miana leaves against test bacteria is determined by the liquid dilution method. Expectorant activity testing was determined by measuring the viscosity of mucus viscosity of cow intestine treated with miana leaf extract. The results found that antioxidant activity was influenced by the location where miana leaves grew with an antioxidant potential of IC72 0.072 mg/ml - 0.76 mg/ml. Contaminant bacteria from sputum samples of cough patients are Streptococcus pneumonia, Klebsiella pneumonia, Staphylococcus aureus, Staphylococcus epidermidis and Enterobacter agglomerans. MIC values for contaminant bacteria are 0.1% - 0.75% and MKC values are found between 0.25% - 1.75%. miana leaf extract has the potential as a sputum thinner at a concentration of 0.01% - 0.1%. The recommended dose of miana leaf extract as a cough with phlegm is 1.75% w/v.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2025 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.