Objective. The aim of this study was to investigate whether platelet indices-mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT) would be useful as noninvasive biomarkers for determining the severity of endometriosis. Methods. A retrospective review of the medical charts of 164 patients diagnosed with endometriosis and who were operated on between 2001 and 2013 was performed. The stage of endometriosis was determined according to revised American Society for Reproductive Medicine criteria. Results. In patients with advanced endometriosis (Stages 3-4), PLT, PCT levels were found to be significantly higher and MPV, PDW values to be significantly lower when compared to initial endometriosis (Stages 1-2). In addition, there was a significant positive correlation between PLT (r: 0.800, P: 0.001) and PCT (r: 0.727, P: 0.002) and the inflammatory marker white blood cell count (WBC). Conclusion. Our finding may not sufficient for employing platelet indices solely in this differential diagnosis, but our finding could provide a suggestion for clinical physicians so that attention is paid to the value of platelet indices and that these may be taken into account when making decisions about the initial or advanced stages of endometriosis.

Visfatin was the most important risk factor for occurrence of EC other than, age, BMI, Diabetes Mellitus and other biochemical factors like HDL, LDL, TG, TC. Clearly, there are largely unknown aspects of visfatin pathophysiology in EC and require further study.

Objective: The purpose of study was to investigate erythrocyte indices in patients with preeclampsia. Materials and Methods:The study population consisted of 102 patients with preeclampsia (49 mild, 53 severe preeclampsia) and 98 control pregnant patients. For the entire study population, red blood cell indices, including baseline mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), red cell distribution width (RDW), and red blood cell (RBC) were measured by using an automatic blood counter. Results: In the preeclampsia group, the median RDW was 15% (13.8-16.57), whereas in the control group it was 13.9% (13-15.6) (p<0.01). On the other hand, the mean MCV value was 80.42±7.86 (fL) in preeclampsia group and 83.88±2.31 (fL) in control group (p=0.003). Besides, the mean MCHC value was 33.66±1.71 (g/dL) in preeclampsia group and 33.09±1.48 (g/dL) in control group (p=0.012). However MCH and RBC values were not statistically different between the groups. (p>0.05) Moreover, subgroup analysis revealed that RDW levels were significantly increased in preeclampsia subjects than in mild preeclampsia patients (15.4% (13.9-17.45) vs 14.3% (13.7-15.7), p=0.031), MCV levels were decreased (78.81±7.91 (fL) vs 82.16± 7.43 (fL), p=0.03), RBC values were increased (4.16 (3.79-4.85)x(10 12 /L) vs 3.82 (3.45-4.34)x(10 12 /L), (p=0.006)) in patients with severe preeclampsia when compared to the patients with mild preeclampsia. In the receiver operator characteristic (ROC) analysis of subjects with and without preeclampsia, RDW and MCV showed high predictive values (p<0.01). Besides, in ROC analysis of preeclampsia patients with different severities, RDW and RBC showed the ideal predictive values (p=0.006, p=0.031, respectively). Conclusion: Our study results revealed that among the red blood cell indices, only increased RDW values were associated with both the presence and the severity of preeclampsia.Amaç: Bu çalışmanın amacı preeklampsi tanısı konmuş hastalarda eritrosit indekslerini araştırmaktır. Gereç ve Yöntemler: Bu çalışmaya 102 preeklampsi (49 hafif ve 53 şiddetli preeklampsi olmak üzere) ve 98 kontrol hastası dahil edilmiştir. Tüm çalışma grubunda eritrosit indeksleri olan ortalama korpuskular hacim (MCV), ortalama korpuskular hemoglobin (MCH), ortalama korpuskular hemoglobin konsantrasyonu (MCHC), eritrosit sayımı ve eritrosit dağılım genişliği değerleri otomatik kan sayım cihazı ile ölçüldü.Ad dress for Cor res pon den ce/Ya zış ma Ad re si:

Results:In both the groups, early-and late-onset changes in the pulsatility index (PI) and other Doppler indices for UA, UtA, and MCA were similar. In addition, time elapsed till delivery, fetal mortality, and maternal morbidity in both the groups were not statistically significant (p>0.05). However, maternal side effects such as tachycardia was more frequent (p<0.05) in the ritodrine group. Besides, in the ritodrine group, anxiety was only minimally observed. Conclusion:Nifedipine and ritodrine used as tocolytic agents did not significantly alter early-and late-onset changes in Doppler ultrasonography parameters in fetal and fetomaternal circulation. (J Turk Ger Gynecol Assoc 2015; 16: 80-5) Keywords: Doppler ultrasonography, tocolysis, umbilical artery, uterine artery, middle cerebral artery Received: 10 October, 2014 Accepted: 08 March, 2015 Comparison of effects of nifedipine and ritodrine on maternal and fetal blood flow patterns in preterm labor Abstract Metarial and MethodsSixty pregnant women, who applied to our clinic because of preterm labor and were aged between 18 and 44 years, were included. The subjects were enrolled after institutional ethic committee approval. Informed consent was obtained from all participants. The research was conducted in women who fulfilled the following admission criteria: pregnant with a single fetus of 24-36-week gestation; fetus with intact amniotic membranes; and experiencing two or more painful and persistent uterine contractions in 10 minutes, as established by tococardiography. These contractions could not be controlled after 2 hours of bed rest and resulted in changes in the cervix (at least 2 cm cervical dilatation and 75% ripening) (8,9). In all cases, fetal heart rates were recorded by ultrasonography or tococardiography. All patients included in the present study were in the latent phase of labor. Patients having cervical dilatation greater than 5 cm and effacement of 80% were not included in the present study. In addition, pregnant women with a concomitant morbidity such as heart, lung, or thyroid disease; high blood pressure; diabetes or infectious disease; an obstetric morbidity (e.g., pre-eclampsia, premature rupture of membranes, polyhydramniosis, gestational diabetes mellitus, intrauterine growth restriction, chorioanmionitis, or acute fetal distress); multiple pregnancies; or fetal malformations and patients who could not tolerate treatments were excluded from the present study. Demographic features and obstetric histories were recorded. Age, gravidity, parity, abortion, frequency of uterine contractions in 10 minutes, cervical dilatation, ripening parameters, and Bishop scores of patients were recorded. Fetal biometry and estimated fetal weight were evaluated via obstetric ultrasonography. Monitorization of uterine contractions and fetal cardiac activity were performed using a tococardiography device CMS 800G (Contec Medical System, China) or Wallach Sonicaid Team (Wallach Surgical devices, USA) for 20 minutes. Tocolysis was started when regular ...

Aim. The purpose of this study was to investigate factors affecting the success of different treatment modalities for the management of ectopic pregnancy (EP). Methods. One hundred and ninety-seven patients with EP, were included in the study. Patients were treated with either intramuscular methotrexate (Mtx) or surgical treatment. Results. Mtx was applied in 97 (49.2%) patients. In 67 patients (69.1%), a single dose of Mtx and in 30 patients (30.9%) a multiple dose of Mtx was applied. Forty-seven (70.14%) patients were successfully treated with a single-dose Mtx. In the multiple-dose group, the success rate was 70% (21/30 patients). The difference between the success rates was not statistically significant. When the initial serum βhCG value was <1000 mIU/mL, the overall success rate of Mtx treatment was determined to be 86.11%; however, the rate decreased to 42.3% when the βhCG value was >3000 mIU/mL. On the other hand, if the EP mass diameter was <25 mm, the success rate was 89.28% and decreased to 52.63% when it was ≥25 mm. Conclusion. The results of the study showed that single-dose treatment with Mtx could be as successful as multiple doses. Overall success of Mtx treatment depended on initial βhCG value and EP mass diameter.