BACKGROUNDThe Global Initiative for Chronic Obstructive Lung Disease (GOLD) recently defined COPD as "A common preventable and treatable disease characterised by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response of the airways and the lung to noxious particles or gases." Though the COPD patients mostly present with the features of acute respiratory infections (productive cough, dyspnoea, etc.), there may be a number of metabolic derangements arising out of the disease process or as a consequence of the therapy instituted like dyselectrolytaemia.This study is aimed at comparing the levels of Sodium, Potassium and Magnesium in Stable COPD and COPD Exacerbation (AECOPD) Patients.

BACKGROUND Tuberculosis is one of the major infectious diseases affecting the global population. It ranks alongside HIV as a leading cause of death worldwide. Around 9.6 million people were estimated to be suffering from TB in 2014, out of which 480000 were cases of multi drug resistant TB (MDR-TB) Tuberculosis most commonly affects the lungs. It can involve almost any organ system of the body, the so called extra pulmonary TB. EPTB possess a diagnostic challenge for the clinicians because of lack of specific and usual symptoms of cough. In this study, we have analysed the pattern of EPTB in our center MATERIALS AND METHODS It was a prospective observational study. 60 patients suffering from EPTB were included and these patients were selected on basis of radiological or histological confirmation of TB with or without AFB positivity source of data included physician prescribing records, patient medication profile, laboratory investigations and presentations. Study was conducted over a period of one year. Patients with Pulmonary Tuberculosis (PTB) and HIV were excluded. CONCLUSION Maximum number of patients were in the age group of 21 to 40 years. Males predominantly suffered from the disease. Lymph node TB was the commonest form of EPTB followed by pleural effusion RESULTS There was a slight male preponderance. Lymph node was the commonest site of involvement in EPTB, followed by pleural effusion.

BACKGROUND Tuberculosis (TB) is an infectious disease caused by the organism Mycobacterium tuberculosis. It is one of the leading infectious causes of death worldwide. The aim of the study was to see the adverse drug reactions of the first line anti TB drugs in extr a pulmonary tuberculosis (EPTB) population. The aim of this study was to evaluate the adverse drug reactions to first line antituberculosis drugs in EPTB. MATERIALS AND METHODS The study was conducted in a tertiary care setting. It was a prospective, observational study. 60 patients suffering from EPTB were included. Patients were categorised to receive either category I, Category II DOTS or a private regimen. The data was analysed using SPSS version 20 software. Chi-square test were used for compared proportions. RESULTS Out of 60 patients, 22 (36.66%) developed ADR. The incidence of ADR's were found to be more in females (77.27%) as compared to males (22.72). Incidence of ADR's were maximum in the age group 21-40 years (63.63%). CONCLUSION A knowledge about ADR's is essential for effective management of any disease.