HighlightsA very rare case of large retroperitoneal mucinous cystadenocarcinoma and little-known clinical course of the disease is reported.The disease took unexpectedly aggressive progression despite the small portion of adenocarcinoma for the multiple and large cysts.Informative findings in imaging of primary retroperitoneal mucinous cyst adenocarcinoma, and impressive imaging after recurrence are presented.
A Peutz-Jeghers P-J type polyp is a hamartomatous polyp that occurs in patients with P-J syndrome, but is rarely found as a solitary polyp in non-P-J syndrome patients 1 . There have been some reports of polyposis and cancerous transformation in patients with P-J syndrome, but few reports of solitary P-J type polyps containing cancer foci 2, 3 . We report here a rare case of a colorectal P-J type polyp showing the hamartoma-adenoma-carcinoma sequence in a non-Peutz-Jeghers syndrome patient. Case ReportA 48-year-old woman was admitted to our hospital for medical examination. Colonoscopy Abstract : Peutz-Jeghers P-J syndrome is an inherited disorder characterized by multiple hamartomatous gastrointestinal polyps, mucocutaneous pigmentation, and an increased risk of both digestive tract and non-digestive tract cancers. P-J type polyps are characteristic of P-J syndrome but rarely present as solitary polyps. Though cancerous lesions frequently develop from polyposis in P-J syndrome, reports of malignancy in solitary colorectal P-J type polyps are rare ; our literature search identi ed only two examples. This report describes a non-Peutz-Jeghers syndrome patient with a solitary P-J type polyp showing the hamartoma-adenoma-carcinoma sequence.
: This study aimed to evaluate the frequency, distribution, and corresponding histology of MUC1 expression in colorectal cancer and examine its association with clinicopathological factors. MUC1 expression was con rmed in 86 of 169 surgically resected colorectal cancers 51% , although the ratio of MUC1-positive cells was less than 5% in 33 cases 20% , 5-50% in 46 cases 27% , and greater than 50% in only 7 cases 4% . None or less than 5% of MUC1 expression cases were classi ed as L-group cancers 116 cases, 69% , while cancers showing higher than 5% expression were classi ed into the H-group 53 cases, 31% . Analysis of the intratumoral distribution of positive cells in the H-group cases showed MUC1 expression distributed predominantly in the upper layers in 3 cases 6% , in the lower layers in 18 cases 34% , and in all layers in 32 cases 60% . MUC1 expression was observed in various histomorphological cancer forms, but the most frequent expression was noted in the monolayer cuboidal pancreatobiliary-type neoplastic glands. Considering the relationship between MUC1 expression and clinicopathological factors, H-group cases demonstrated signi cantly larger lesions showing a greater number of ulcerated-type cancers, deeper invasion, poorer differentiation, higher frequency of budding, and higher rate of lymph node metastasis than L-group cancers. Furthermore, there was a difference of 10% between the H-group and L-group with regard to the frequency of relapse/tumor mortality three years after surgery. In colorectal cancer, MUC1 expression increases with progression of the tumor indicating that it is one of the useful indicators of malignancy and may facilitate appropriate treatment regimens ; however, as its expression is heterogeneous and localized, it will be necessary to con rm the state of MUC1 expression by case.
Background A self-expandable metal stent is often placed as a bridge to elective surgical treatment of left-sided malignant obstruction of the colon because it allows for primary anastomosis without the need for a temporary stoma, which has a positive impact on the patient’s quality of life. However, although a relatively safe procedure, colonic stenting can have complications that require emergency surgery. This case report describes a rare case of abdominal compartment syndrome that occurred as a complication during colonic stenting. Case presentation: The patient was a 72-year-old woman who presented complaining of several days of constipation and loss of appetite. Computed tomography of the abdomen revealed obstruction of the sigmoid colon by a tumor. There were no symptoms or computed tomography findings to suggest perforation. Therefore, an attempt was made to insert a self-expandable metal stent. Acute respiratory disturbance and a change in consciousness occurred during the stenting procedure, with marked abdominal distention. Abdominal compartment syndrome was diagnosed and treated by decompressive laparotomy. Conclusions To the best of our knowledge, this is the first reported case of abdominal compartment syndrome as a complication of colonic stenting. The possibility of abdominal compartment syndrome should be considered if acute respiratory disturbance or altered consciousness occurs during placement of a colonic stent.
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