Introduction:Uterine cervix tumors have an invasive nature, with the capacity to proliferate to surrounding organs such as the vagina, bladder, and rectum, as well as the capacity for dissemination and involvement of structures distant from its place of origin. According to the International Federation of Gynecology and Obstetrics, patients with stages IB I, IB I microscopic (small dimension <4 cm) are indicated for radiotherapy or adjuvant chemoradiotherapy with cisplatin (40 mg/m2). However, cisplatin has side effects such as hematological implications (anemia, neutropenia, and thrombocytopenia), gastrointestinal disorders (nausea, vomiting, diarrhea, constipation), and fatigue. Zingiber officinale contains bioactive compounds that act on pregnancy and postoperative nausea, chemotherapy-induced nausea and vomiting, and also in the management of fatigue, myalgia, and insomnia. This study aimed to evaluate the effects of ginger on chemotherapy-induced nausea and vomiting in patients with cervical cancer undergoing treatment with cisplatin and radiotherapy.Methods and analyses:A randomized intervention clinical and controlled trial with a triple-blind design is described, comparing the effects of institutional antiemetic therapy alone, as well as in combination with 2 different ginger concentrations.Ethics and dissemination:Due to the nature of the study, we obtained approval from the Division Ethics Committee of Liga Contra o Câncer. All participants signed an informed consent form prior to randomization. The results of this study will be published in peer-reviewed journals. The data collected will also be available in a public repository of data.Trial registration number:This study is registered in the Brazilian Registry of Clinical Trials under number RBR-47yx6p9. This study was approved by the Division Ethics Committee of Liga Contra o Câncer under CAAE 40602320.0.0000.5293.
Objective: to map the knowledge about SARS-CoV-2 infection in patients with cancer in terms of clinical manifestations, treatment, and prognosis. Method: a scoping review based on the Joanna Briggs Institute theoretical framework, registered in the Open Science Framework (osf.io/64ems/). A search was carried out in nine databases and virtual libraries in June and July 2020. Results: twenty-five articles were selected that answered the guiding question, demonstrating that the neoplasm most affected by the infection was the lung, and the main clinical manifestations were fever, cough, dyspnea, diarrhea, and fatigue. Regarding treatment, antivirals and antibiotics were the most mentioned. All articles cite the vulnerability of patients with cancer diagnosed with COVID-19, with a mortality rate of 21-30% in most articles and a prognosis for progression to severe forms of the disease. Still, most patients were cured, although in severe cases they worsened, compared to the general population. Conclusion: this study demonstrated insecurity in disease treatment due to the variety of medications used and the uncertainty about whether to continue neoplastic treatment during this period.
Objective: To outline the clinical-epidemiological profile of patients submitted to Percutaneous Coronary Intervention in a Reference Hospital in Urgent Cardiology Clinic of the state of Rio Grande do Norte. Method: This is a descriptive, exploratory, prospective study with a quantitative approach developed in a Brazilian University Hospital with patients submitted to Percutaneous Coronary Intervention. Data collection occurred between April and October 2017. Results: The sample consisted of 222 patients, of whom 58.10% underwent Elective Percutaneous Coronary Intervention and 41.89% were primary, 65.3% males, with a mean age of 62.7. In comorbidities “Hypertension”, “Acute Myocardial Infarction”, “Current Smoking” and “Physical Inactivity” were highlighted. Conclusion: In the elective patients, there was a high prevalence of risk factors and in patients with urgent cases, high time of total ischemia. It is necessary to create strategies to structure the care line, to improve the effectiveness of treatment and to minimize adverse outcomes.
Objetivo: analisar aspectos epidemiológicos e angiográficos de pacientes submetidos à Angioplastia Transluminal Coronariana eletiva em um hospital de referência em cardiologia do estado do Rio Grande do Norte. Métodos: trata-se de uma pesquisa exploratória, descritiva, transversal com abordagem quantitativa. A coleta de dados ocorreu de abril/2017 a outubro/2017. Resultados: foram incluídos no estudo 129 pacientes, destes 65,8% eram do sexo masculino. O stent farmacológico foi mais utilizado nos procedimentos com 79 (61,2%). A via femoral predominou entre os dois sexos, com 29 (65,9%) entre mulheres e 54 (63,5%), nos homens.Conclusões:nota-se predomínio de pacientes do sexo masculino, idosos, baixo grau de escolaridade, pardos, casados e aposentados. A análise angiográfica constitui-se de pacientes com predominância de implantação de um (1) stent do tipo farmacológico, Descendente anterior e Coronária direita como coronárias tratadas, sendo a punção de acesso com maior prevalência a por via femoral.Descritores: Intervenção coronária percutânea; Angioplastia; Infarto do miocárdio; Doenças cardiovasculares; Reperfusão miocárdica.PATIENTS SUBMITTED TO CORONARY TRANSLUMINAL ANGIOPLASTY: EPIDEMIOLOGICAL AND ANGIOGRAPHIC ANALYSISObjective: to analyze epidemiological and angiographic aspects of patients submitted to elective Coronary Transluminal Angioplasty at a referral hospital in cardiology in the state of Rio Grande do Norte. Methodology: This is an exploratory, descriptive, transversal research with a quantitative approach. Data collection occurred from April / 2017 to October / 2017. Results: 129 patients were included in the study, of which 65.8% were male. The pharmacological stent was more used in the procedures with 79 (61.2%). The femoral route predominated between the two sexes, with 29 (65.9%) between women and 54 (63.5%), in men. Conclusions: a predominance of male patients, elderly, low educational level, pardos, married and retired people. Angiographic analysis consists of patients with a predominance of implantation of one (1) stent of the pharmacological type, Anterior descending and Right coronary as treated coronaries, being the access puncture with greater prevalence to the femoral route.Descriptors: Percutaneous coronary intervention, Angioplasty, Myocardial infarction, Cardiovascular diseases, Myocardial reperfusion.PACIENTES SUBMETIDOS A LA ANGIOPLASTIA TRANSLUMINAL CORONARIANA: ANÁLISIS EPIDEMIOLÓGICA Y ANGIOGRÁFICAObjetivo: analizar aspectos epidemiológicos y angiográficos de pacientes sometidos a la Angioplastia Transluminal Coronariana electiva en un hospital de referencia en cardiología del estado de Rio Grande do Norte. Metodology: setrata de una investigación exploratoria, descriptiva, transversal con abordaje cuantitativo. La recolección de datos ocurrió de abril / 2017 a octubre / 2017. Resultados: fueron incluidos en el estudio 129 pacientes, de estos 65,8% eran del sexo masculino. El stent farmacológico fue más utilizado en los procedimientos con 79 (61,2%). La vía femoral predominó entre los dos sexos, con 29 (65,9%) entre mujeres y 54 (63,5%), en los hombres. Conclusiones: se observa predominio de pacientes del sexo masculino, ancianos, bajo grado de escolaridad, pardos, casados y jubilados. análisis angiográfico consistía en pacientes con despliegue predominante de (1) el tipo stent farmacológico antes de la arteria coronaria descendente y la coronaria derecha tratada como la punción de acceso con la prevalencia más alta a través de la arteria femoral.Descriptores: Intervención coronaria percutânea; Angioplastia; Infarto del miocárdio; Enfermedades cardiovasculares; Reperfusión miocárdica.
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