No abstract

Pure transition metal vanadates NiV2O6 and CuV2O6 were successfully prepared via co-precipitation technique as low as at 600 °C. The crystal structure and their phase formation were confirmed by X-ray powdered diffraction. Both the compounds were identified to have a single-phase triclinic structure. The bonding characteristics were studied by FTIR spectroscopy. The temperature dependence of electrical resistivity of these vanadates shows a typical semiconducting nature of NiV2O6 and CuV2O6, consistent with their electronic band structures. The calculated band gap energy values of NiV2O6 and CuV2O6 were found to be 2.42 and 2.0 eV respectively, employing a DRS UV-Visible spectrophotometer. Magnetic susceptibility measurements and calculated Magnetic moments confirm their paramagnetic nature. The photocatalytic efficiency was investigated by photo-degradation of methylene blue (MB) solutions employing solar light and found to be promising photocatalysts.

Isoxazolones are synthesised using easily available, economical and reusable silica (TLC grade) catalyst. High yields are obtained in aqueous reaction system with substrate tolerance without affecting the yield. This multigram scale, purification free method exhibits prospects for a large scale use in future. These compounds were screened for their potential application as quorum quenchers in pathogenic bacteria. The prepared compounds were analysed for quorum quenching (QQ) activity on Gram negative bioreporter strain Chromobacterium violaceum by inhibiting its pigment production i. e. violacein production in a concentration dependent manner. Some Isoxazolone derivatives showed very good quorum quenching activity. Moreover these derivatives also showed very good antibiofilm activity against both Gram negative (Pseudomonas aeruginosa ATCC 27853) and Gram positive (Staphylococcus aureus ATCC 6538) bacterial human pathogens through Quorum Quenching mechanism. Isoxazolones thus have enormous potential to be exploited in the medical field against bacterial infections caused by both Gram negative and Gram positive bacterial human pathogens.

The title compounds (x = 0, 0.3, 0.5, 0.7, 1) with a perovskite structure show phase transitions from semiconductor to semimetallic in the range 570-630 K. The compounds exhibit a significant increase of catalytic activity for CO oxidation by B-site substitution of Co 3+ in LaMnO3. LaCoO3 shows the highest activity in this series for CO oxidation while LaMnO 3 shows the least. LaMnO 3 is antiferromagnetic and with Co 3+ substitution a decrease in saturation magnetization is observed. -(SALKER*, A. V.; VAZ, T.; Indian J.

The emerging nano biosystems are competent in diagnosis, drug delivery, and monitoring of therapeutic response. Both imaging and therapeutic functions can be achieved by using nanoplatforms. These nanoplatforms promise to revolutionize the medical management of many personalized illnesses. The well-developed surface chemistry of iron oxide (Fe3O4) makes it easy to charge them with pharmaceutics, promoting them as nanoplatforms for building up nanoparticle-based drug delivery systems. The strategy to design multifunctional Fe3O4 conjugates with bioactive molecules of plant origin to show enhanced activity is reported here. The conjugation reveals the magnetic Fe3O4 core nanoparticle surface readily link to hydroxyl sites of the Dextrin molecule, which further conjugate to conjugated with Curcumin and D-Limonene, which are powerful anti-cancer, anti-inflammatory, and antioxidant agents. The structural, morphological, optical, and magnetic properties were analyzed by X-ray diffraction, FT-Infrared, HR-Tunneling Electron Microscopy, and Vibrating Sample Magnetometer techniques. The potential drug loading was measured as Drug Entrapment Efficiency using UV-Vis spectroscopy. The antibacterial property was tested on the bacterium S. aureus and E. coli. Fe3O4-Dextrin nanoconjugates proved to be efficient for loading and stabilizing Curcumin and Limonene. Thus, multifunctional Fe3O4 conjugates are explored as exciting nano-drug carriers for targeted drug delivery.