A motivating and fun activity for students in introductory chemistry has been designed to increase familiarity with the chemical elements, symbols, and atomic numbers in the periodic table. This activity, Elemental Knock-Out, is a table tennis game, and the gameplay is adapted from a box grid baseball game. Playing in teams for fun and enjoyment, students work cooperatively with others to compete against an opposing team. The game is designed for first-year undergraduate students. The cost of one set of game materials is less than $50. The average time required to complete one game, i.e., to become familiar with the chemical elements and atomic numbers, is about 120 min for a class of 60 students. This game was implemented with 118 students including different grade classes. The results were interpreted through poll and quiz before and after the activity. The results of the study revealed that most of the students had positive impressions of the game and considered it to be a fun way of interacting with the concepts. The quiz test also showed an increase of average score of the students by playing the game. Table tennis is a sport that anybody at any age can play. Therefore, this game should facilitate the promotion of knowledge of chemistry, e.g., the periodic table of the elements, to the target student group.

In this work, we present a Ag@Au nanoprism-metal-organic framework-paper based glucose sensor for rapid, sensitive, single-use and quantitative glucose determination in human serum. To achieve painless measurement of glucose with a non-invasive detection methodology, this biosensor was further tested in human urine. In this approach, a new hybrid-Ag@Au nanoprism loaded in close proximity to micrometer sized coordination polymers as phosphorescent luminophores significantly enhanced the emission intensity due to metal-enhanced phosphorescence and worked as reaction sites to support more dissolved oxygen. Reports of enhanced phosphorescence intensity are relatively rare, especially at room temperature. The true enhancement factor of Ag@Au-phosphorescent metal-organic frameworks on paper was deduced to be 110-fold, making it a better optical type glucose meter. The results demonstrate the validity of the intensity enhancement effect of the excitation of the overlap of the emission band of a luminophore with the surface plasmon resonance band of Ag@Au nanoprisms. Ag@Au nanoprisms were used not only to improve the detection limit of glucose sensing but also to extend the glucose sensing range by enhancing the oxygen oxidation efficiency. The oxidation of glucose as glucose oxidase is accompanied by oxygen consumption, which increases the intensity of the phosphorescence emission. The turn-on type paper-based biosensor exhibits a rapid response (0.5 s), a low detection limit (0.038 mM), and a wide linear range (30 mM to 0.05 mM), as well as good anti-interference, long-term longevity and reproducibility. Finally, the biosensor was successfully applied to the determination of glucose in human serum and urine.

In this study, a turn‐on paper‐based optical analytical system with a rapid, sensitive and quantitative response for glucose was developed. The luminescence sensing material, crystalline iridium(III)‐Zn(II) coordination polymers, or Ir‐Zne, was grown electrochemically on stainless steel mesh and then deposited on filter paper. This sensing substrate was subsequently built up under glucose oxidase encapsulated in hydrogel and then immobilized on egg membrane with the layer‐by‐layer method. Once the glucose solution was dropped onto the paper, the oxygen content was depleted simultaneously with a concomitant increase in the phosphorescence of Ir‐Zne. The detection limit for glucose was 0.05 mM. The linear dynamic range for the determination of glucose was 0.05–8.0 mM with a correlation coefficient (R2) of 0.9956 (y=68.11 [glucose]−14.72). The response time was about 0.12 s, and the sample volume was less than 5 μL. The effects of mesh size, buffer concentration, pH, enzyme concentration, temperature, and interference, and the stability of the biosensor, have also been studied in detail. Finally, the biosensor was successfully applied to the determination of glucose in human serum.

A paper-based method with selectivity and a wider linear range for the detection of l-Cys in serum using DTNB-modified Ag nanoprisms (AgP-DTNB).