The 2018 CrossFit Open (CFO) was the initial stage of an annual competition that consisted of five weekly workouts. Current evidence suggests that a variety of fitness parameters are important for progressing beyond this stage, but little is known about which are the most important. To examine relationships between CFO performance, experience, and physiological fitness, sixteen experienced (>2 years) athletes (30.7 ± 6.9 years, 171 ± 12 cm, 78.0 ± 16.2 kg) volunteered to provide information about their training and competitive history, and then complete a battery of physiological assessments prior to competing in the 2018 CFO. Athletes’ resting energy expenditure, hormone concentrations, body composition, muscle morphology, cardiorespiratory fitness, and isometric strength were assessed on two separate occasions. Spearman correlations demonstrated significant (p < 0.05) relationships between most variables and performance on each workout. Stepwise regression revealed competition experience (R2 = 0.31–0.63), body composition (R2 = 0.55–0.80), vastus lateralis cross-sectional area (R2 = 0.29–0.89), respiratory compensation threshold (R2 = 0.54–0.75), and rate of force development (R2 = 0.30–0.76) to be the most common predictors. Of these, body composition was the most important. These fitness parameters are known targets with established training recommendations. Though preliminary, athletes may use these data to effectively train for CFO competition.
This investigation examined anthropometric, hormonal, and physiological differences between advanced (
Methylliberine (Dynamine®; DYM) and theacrine (Teacrine®; TCR) are purine alkaloids purported to have similar neuro-energetic effects as caffeine. There are no published human safety data on DYM, and research on TCR is limited. The purpose of this study was to examine the effect of four weeks of DYM supplementation with and without TCR on cardiovascular function and blood biomarkers. One-hundred twenty-five men and women (mean age 23.0 yrs, height 169.7 cm, body mass 72.1 kg; n = 25/group) were randomly assigned to one of five groups: low-dose DYM (100 mg), high-dose DYM (150 mg), low-dose DYM with TCR (100 mg + 50 mg), high-dose DYM with TCR (150 mg + 25 mg), and placebo. Regardless of group and sex, significant main effects for time were noted for heart rate, systolic blood pressure, and QTc (p < 0.001), high-density lipoproteins (p = 0.002), mean corpuscular hemoglobin (p = 0.018), basophils (p = 0.006), absolute eosinophils (p = 0.010), creatinine (p = 0.004), estimated glomerular filtration rate (p = 0.037), chloride (p = 0.030), carbon dioxide (p = 0.023), bilirubin (p = 0.027), and alanine aminotransferase (p = 0.043), among others. While small changes were found in some cardiovascular and blood biomarkers, no clinically significant changes occurred. This suggests that DYM alone or in combination with TCR consumed at the dosages used in this study does not appear to negatively affect markers of health over four weeks of continuous use.
Under the conditions of the present study, sleep-deprived persons are not at a greater risk for a decline in rectal temperature (ie, a hypothermic afterdrop) during rewarming from cold air.
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