Sensitisation of the mesoaccumbens dopamine response to nicotine is influenced by pre-treatment dose and the strain of rats used. It is not related directly to the expression of sensitised locomotor responses to the drug and, therefore, may be implicated in other psychopharmacological properties of the drug, including dependence.

When compared with pesticide pollution from other sources and pollution by other agents, the hazards of atmospheric pollution by pesticides appear relatively insignificant. The high persistency in the environment observed especially with the organochlorines suggests that there could be a gradual accumulation of residual pesticides in the atmosphere. Thus, in addition to the function of redistributing pesticides by air currents and aerial drifts, the atmosphere may become a major reservoir for drift prone finely divided particulate pesticides and highly volatile compounds.Indiscriminate aerial spraying should be avoided. A more selective approach should be adopted whereby forest areas are sprayed without contaminating streams, lakes and inland waters. Improvement in spraying devices are needed such that pesticides are more precisely delivered to target. Direct spraying of water bodies should be avoided as much as possible. Treatment of waste water for pesticide removal or neutralization

No abstract

No abstract