This paper highlights the gap in the use of genomic data of Africans for global research efforts for disease cures. Genomic data represents an important tool used in disease research for understanding how diseases affect several populations and how these differences can be harnessed for the development of effective cures especially vaccines that have an impact at the genetic level e.g., RNA vaccines.This paper then provides a review of global genomic data status where three continents are reported to be the major contributor of genomic data to repositories used for disease research and the development of vaccines and medicines around the world.We reviewed the most recently published information about genetic data inclusiveness of populations, explaining how genomic data of Africans is lacking in global research efforts that cater towards the eradication of pandemics via the development of vaccines and other cures. We also discuss the implication of this non-inclusiveness for global disease burdens and indicate where changes need to be made in the last part of the paper.Lastly, the entire centers on some general policy recommendations to fully include African genomic data in such global genetic repositories. These recommendations can be implemented in African countries to improve genetic data collection, storage, and usage policies.
This paper examines the large-scale path loss models for an indoor corridor environment at frequencies of 28 and 38 GHz. The measurement environment consists of an indoor corridor with both line-of-sight (LOS) and non-line of sight (NLOS) scenarios using vertical–vertical (V–V) and vertical–horizontal (V–H) antenna polarizations. The single-frequency close-in (CI), floating intercept (FI), free space large-scale path loss models and measured data from the measurement campaign were used to evaluate the performance analysis. The paper also focuses on various parameters, such as standard deviation, path loss exponent (PLE), accuracy, simplicity, and stability of the models. The analysis focuses on the peculiarity of the effect of the wall proximity on the path loss parameters as well as comparisons with the parameters in some of the reviewed literature studies. The FI and CI models produce comparable results for both antenna polarizations and clearly fit with the measured path loss. The PLE, with the highest value of 3.33 at 38 GHz (V–H), is much higher in the NLOS scenario with V–H polarization due to the signal degradation along the path from the transmitter (Tx) to the receiver (Rx). This is because there is no direct LOS between the Tx and Rx antennas. The Rx only relies on signal diffractions and reflections from obstacles as it transmits through the path from the Tx antenna. The path loss measurements and model analysis presented here are useful in designing 5G wireless communication systems for indoor environments, particularly for power budget calculations.
The importance of the path loss in millimeter wave channel propagation cannot be taken for granted in terms of deployment, design, performance assessment, and planning. The path loss helps to determine the network’s geographic coverage. Although many path loss models, including statistical and empirical models based on measurement and linear regression, have been proposed by various researchers, high fidelity is required to determine the performance of the wireless network’s channel. This research validates the improved version of the well-known close in (CI) and floating intercept (FI) path loss models at frequency bands of 28 and 38 GHz. The measurement surroundings comprised of an enclosed passageway with vertical-horizontal (V-H) and vertical-vertical (V-V) antenna polarizations. One of the key findings of this study is that the enhanced versions of these models typically perform better in terms of consistency than the standard models thereby justifying their high accuracy level. The improved versions of the CI and the FI models demonstrate a significant improvement for various antenna polarizations. The mean prediction error (MPE) and standard deviation error (SDE) also show how precisely and accurately the improved models predict the path loss. Additionally, the improved models provide the reasonable responsiveness and uniformity of the parameters with the change in the antenna polarization and lower the shadow fading’s standard deviation in LOS as well as NLOS situations. The results confirm that the modified versions of CI and FI models predict path loss better in an enclosed environment for 5G networks.
Previous studies have shown that there is increased mortality of cerebrovascular diseases such as stroke among Canadian women. The morbidity of stroke is also higher among Canadian women because they are less likely to recover from stroke, and they generally tend to have a greater disability from a stroke when compared to men. In order to help minimize these issues, six interventional strategies were evaluated using four criteria: 1) the evidence-based criterion, 2) the socioeconomic-based criterion, 3) the ethics-based criterion, and 4) the sustainable-based criterion. Upon analysis, two alternative interventional strategies were recommended: increased public awareness of stroke symptoms and increased public awareness of stroke risk factors among Canadian women.
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