In a double-blind randomized placebo trial, the effect of the powdered rhizome of ginger (Zingiber officinale) was tested on seasickness. Eighty naval cadets, unaccustomed to sailing in heavy seas reported during voyages on the high seas, symptoms of seasickness every hour for 4 consecutive hours after ingestion of 1 g of the drug or placebo. Ginger root reduced the tendency to vomiting and cold sweating significantly better than placebo did (p less than 0.05). With regard to vomiting, a modified Protection Index (PI) = 72% was calculated. Remarkably fewer symptoms of nausea and vertigo were reported after ginger root ingestion, but the difference was not statistically significant. For all symptom categories, PI = 38% was calculated.

Repair of defects of the ossicular chain with GIC is an easy, efficient, quick, and inexpensive method, which ought to be kept in mind for future middle ear surgery. No complications in the middle ear were related to GIC.

No abstract

An improved thin-layer chromatographic assay for monitoring phospholipid ratio in mucus was used to study the respiratory system distribution of children with and without secretory otitis media. Phosphatidylcholine, phosphatidylethanolamine and sphingomyelin abound, while only traces of other phospholipids are found. Analyses show more sphingomyelin and less phosphatidylcholine in the Eustachian tube and nose than in the lung, while phosphatidylethanolamine has about the same distribution. The phosphatidylcholine/sphingomyelin ratio is significantly less in Eustachian tube mucus from children with secretory otitis media compared with otologically healthy children, which indicates a different secretory pattern of the cells in the Eustachian tube of these children. The distribution of phospholipids in middle ear secretion is different from the distribution obtained from the Eustachian tube in children with secretory otitis media thus verifying a clearance 'blocking' of the tube caused by the disease.

The principle of sonotubometry for recording the opening of the Eustachian tube is based on the assumption that this opening increases the sound transmission from the nasopharynx to the external ear canal. However, the clinical validity of the method remains to be documented. In the present study the results in 37 normal ears were compared with those of 11 ears which showed signs of Eustachian tube dysfunction. In these glue was found in the middle ear at a subsequent myringotomy. In 13 of the subjects a comparison was made of the signals picked up from the ear canal and from the contralateral nostril. It was concluded that the interpretation of the signals from the ear canal is very complicated. They may be due to an opening of the Eustachian tube, but they may also be caused by a change of the acoustic conditions in the nasopharynx during the swallowing procedure. Despite the fact that this test principle in theory is ideal, much research seems to be required before the clinical value of the method can be confirmed.