The disease that was recently discovered in December 2019 is COVID-19, this disease is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Everyone can be infected, one of them is pregnant women, pregnant women are susceptible to infection with this virus because of changes in the body's physiology that can impact on the immune system. This study aimed to find out the results of ALC and NLR in 3rd trimester pregnant women who were confirmed positive for SARS-CoV-2 at Prof. Dr. R. D. Kandou. The study was conducted with a retrospective approach, using secondary data in the form of medical record status of 3rd trimester pregnant women who were confirmed positive for SARS-CoV-2 at RSUP Prof. Dr. R. D. Kandou. From 26 pregnant women who were treated at Prof. Dr. R. Kandou from July to September 2020 found 22 patients (85%) with normal ALC and 4 patients (15%) had a decrease in ALC. For NLR, it was found that 16 patients (62%) had an NLR ≥ 3.13, and 10 patients (38%) had an NLR < 3.13. In conclusion, from 26 pregnant women who were treated in July-September 2020, the ALC results obtained were more patients with normal ALC levels, namely 22 patients (85%), while the NLR results obtained were more patients who had NLR ≥ 3.13, namely 16 patients (62%).Keywords: 3rd trimester pregnant women, SARS-CoV-2, Absolute Lymphocyte Count, Neutrophil-Lymphocyte Ratio Abstrak: Penyakit yang baru saja ditemukan pada bulan Desember 2019 adalah COVID-19, penyakit ini disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Semua orang dapat terinfeksi salah satunya wanita hamil, wanita hamil rentan terinfeksi virus ini karena adanya perubahan fisiologi tubuh yang dapat berdampak pada sistem kekebalan tubuh. Tujuan penelitian ini untuk mengetahui hasil gambaran ALC dan NLR pada wanita hamil trimester 3 yang terkonfirmasi positif SARS-CoV-2 di RSUP Prof. Dr. R. D. Kandou. Jenis penelitian yang digunakan bersifat deskriptif dengan pendekatan retrospektif, yaitu menggunakan data sekunder berupa data dari status rekam medis pasien wanita hamil trimester 3 yang terkonfirmasi positif SARS-CoV-2 di RSUP Prof. Dr. R. D. Kandou. Dari 26 wanita hamil yang dirawat di RSUP Prof. Dr. R. Kandou periode Juli - September tahun 2020 didapatkan 22 pasien (85%) dengan ALC normal dan 4 pasien (15%) lainnya mengalami penurunan pada ALC. Untuk NLR didapatkan 16 pasien (62%) memiliki NLR ≥ 3,13, dan 10 pasien (38%) memiliki NLR < 3,13. Sebgai simpulan, dari 26 wanita hamil yang dirawat pada bulan Juli-September 2020, hasil ALC yang didapatkan lebih banyak pasien memiliki kadar ALC normal yaitu 22 pasien (85%), sedangkan hasil NLR yang didapatkan lebih banyak pasien yang memiliki NLR ≥ 3,13 yaitu 16 pasien (62%).Kata kunci : wanita hamil trimester 3, SARS-CoV-2, Absolute Lymphocyte Count, Neutrophil- Lymphocyte Ratio
Gastroschisis is the most common congenital defect in the abdominal wall in the last 30 years. This may be related to increased incidence of prematurity and increased survival rate of premature babies. Defects in the abdominal wall usually occur less than 4 cm, located at the junction of umbilicus and normal skin.Relatively young maternal age (<21 years), as well as habits of consuming alcohol and drugs can increase the risk of gastroschisis.Diagnosis can be confirmed at prenatal stage by using USG, and at postnatal stage. Initial treatment consists of fluid resuscitation, oxygenation, decompressed nasograstic tube (NGT), and hypothermia prevention. In conclusion, gastroschisis needs immediate treatment by prevention of hypothermia in infants, administration of fluid and oxygen, and closure of defect. The overall survival rate is quite good and the prognosis depends on the condition of the gut at birth. Keywords: gastroschisis Abstrak: Gastroschisis merupakan defek kongenital pada dinding abdomen yang paling umum ditemukan dalam 30 tahun terakhir. Hal ini mungkin terkait dengan peningkatan kejadian prema-turitas dan peningkatan kelangsungan hidup bayi prematur.Defek pada dinding abdomen terjadi biasanya kurang dari 4 cm dan terletak di antara sambungan umbilikus dan kulit normal. Usia ibu yang relatif muda (<21 tahun), kebiasaan mengonsumsi alkohol serta obat-obatan dapat mening-katkan risiko terjadinya gastroschisis. Diagnosis dapat ditegakkan saat prenatal dengan USG, dan postnatal. Penatalaksanaan awal meliputi resusitasi cairan, pemberian oksigenasi, pemasangan nasogastric tube (NGT) dekompresi, serta mencegah terjadinya hipotemia. Simpulan tulisan ini ialah gastroschisis memerlukan penanganan segera dengan melakukan pencegahan terjadinya hipotermia pada bayi, pemberian cairan, pemberian oksigenasi, dan penutupan defek. Tingkat kelangsungan hidup secara keseluruhan cukup baik dan prognosis tergantung pada kondisi usus saat lahir.Kata kunci: gastroschisis
Pregnancy is a condition of physiological and mechanical changes in the body that can reduce the ability of the immune system. During pregnancy, the normal changes that occur can be observed on the hematological index. There are studies that have found decreased levels of lymphocytes and monocytes, total leukocytes, increased platelet counts, and increased Hb in pregnant women infected with SARS-CoV-2. This study aimed to determine an overview of leucocytes, differential counting and platelets in 3rd trimester pregnant women. This research is a descriptive type of retrospective study, by collecting secondary data from medical record status. There were 26 samples of pregnant women in trimester 3 who were confirmed positive for SARS-CoV-2, 17 patients (65%) had an increase in the number of leukocytes. Differential counting was decreased stem neutrophils in 13 patients (50%), normal segment neutrophils in 16 patients (62%), decreased lymphocytes in 13 patients (50%), decreased eosinophils in 14 patients (54%), monocytes increased only in 2 patients (8%) and basophils were normal in all patients. 100% normal platelet count in all samples. In conclusion, the hematological features obtained are leukocytosis, decreased stem neutrophils, 62% normal segment neutrophils, lymphopenia, eosinopenia. normal 92% monocytes are normal, basophils and platelets within normal limits.Keywords: SARS-CoV-2, pregnant women, leukocytes, differential counting, thrombocyte Abstrak: Kehamilan merupakan suatu kondisi perubahan fisiologis dan mekanis tubuh yang dapat berdampak pada penurunan kemampuan sistem kekebalan tubuh. Selama kehamilan, perubahan normal yang terjadi dapat diamati pada indeks hematologi. Terdapat penelitian yang menemukan penurunan kadar limfosit dan monosit, total leukosit, peningkatan jumlah trombosit, dan peningkatan Hb pada wanita hamil yang terinfeksi SARS-CoV-2. Tujuan penelitian ini untuk mengetahui gambaran leukosit, differential counting dan trombosit pada wanita hamil trimester 3. Penelitian ini merupakan jenis penelitian deskriptif dengan studi retrospektif, yaitu dengan mengumpulkan data sekunder berupa data dari status rekam medik. Terdapat 26 sampel wanita hamil trimester 3 yang terkonfirmasi positif SARS-CoV-2, 17 pasien (65%) mengalami peningkatan jumlah leukosit. Differential counting yaitu neutrofil batang menurun pada 13 pasien (50%), neutrofil segmen normal pada 16 pasien (62%), limfosit menurun pada 13 pasien (50%), eosinofil menurun pada 14 pasien (54%), monosit meningkat hanya pada 2 pasien (8%) dan basofil dalam jumlah normal pada semua pasien. Jumlah trombosit 100% normal pada semua sampel. Sebagai simpulan, gambaran hematologi yang didapatkan yaitu leukositosis, penurunan neutrofil batang, neutrofil segmen 62% normal, limfopenia, eosinopenia. monosit 92% normal, basofil dan trombosit dalam batas normal.Kata kunci : SARS-CoV-2, wanita hamil, leukosit, differential counting, trombosit
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