Background: The residents’ perceptions of the crime and lack of safety with their neighborhood environment, associated with stress that confers risk for drinking .While many studies have focused on adult drinking, less is known about how subjective neighborhood crime influences drinking during adolescent. We aimed to determine the association of perceived neighborhood crime and youth alcohol use. Study design: A cross-sectional study. Methods: This study was conducted on 1087 university youths from 30 neighborhood clusters in Northeastern Thailand from May 2019 to Mar 2020 .The data were collected by self-administered questionnaire .A multilevel logistic regression model was applied to examine the effect of perceived neighborhood crime on hazardous alcohol use. Results :Most of youths were female, approximately 60.7 %reported hazardous alcohol use, and the average perceived neighborhood crime score was 65.1 (standard deviation, 2.1) .The perceived neighborhood crime was associated with hazardous alcohol use; a 1-unit increase in the scores for perceived neighborhood crime corresponded to a 20 %increase in hazardous alcohol use. The role of perceived neighborhood crime on alcohol use varied among males, but not females. Conclusion :The perceived neighborhood crime plays a role in the increase likelihood of hazardous alcohol use .The consideration of neighborhood crime context is important to design the alcohol preventive and intervention strategies.

This investigation aimed to assess the microbial quality of drinking water produced by drinking water filtration dispenser toll machines (DFTMs) to assess the health risk of DFTM water. A total of 210 samples were randomly collected of 70 DFTMs within a radial distance of 500 metres around Mahasarakham University. The prevalence of Escherichia coli and Staphylococcus aureus in the DFTM water was 54.17% and 16.67% with an average concentration of 1.04 log cfu/ml and 0.26 log cfu/ml, respectively. The risk calculation (using the @Risk program based on drinking water consumption of 2 L/day) indicated that the probability of exposure was 1.67 E-01, while the probability of illness due to E. coli and S. aureus was 2.08 E-03 and 1.58 E-05 and the risk of illness was 1.13 E-03 and 2.64 E-06, respectively. The sanitation status and drinking water quality related to health would be influenced by other pathogens due to the poor hygienic conditions of DFTMs and improper environments.

BACKGROUND: Health literacy (HL) is an important role-play in health risk behaviors such as alcohol drinking and smoking. Inadequate HL in substance use (HLSU) is a barrier to reduce the risk of alcohol and tobacco use. This study aims to investigate the association of HLSU with alcohol consumption and tobacco use among Thai adolescents. Hence, the strengthening of HL program intervention may applied to reduce substance abuse among Thai adolescents. MATERIALS AND METHODS: This was a cross-sectional study conducted on 1087 university students studying in three universities located in northeastern area with multistage sampling methods by geographical areas. The data were collected by self-administered questionnaire. Multiple logistic regression was applied to determine the effect of HLSU of alcohol consumption and tobacco use. RESULTS: Most adolescents were drinkers (60.7%) and about 20.7% were smokers. Approximately 40% of them reported as inadequate HLSU. Adolescents with inadequate HLSU and a high level of positive alcohol expectancies and smoking outcome expectancies (SOE) were more likely to drink alcohol and smoke. Conversely, those who had a high level of negative alcohol drinking and SOE were less likely to consume alcohol and tobacco. CONCLUSION: Adolescents’ alcohol consumption and tobacco use were influenced by HL, hence improving adolescents’ HLSU could help prevent or reduce the risk of drinking and smoking behaviors.

Context: A major social problem among clients with substance use disorders is stigmatization related to health conditions, which contributes to poor mental and physical health circumstances and becomes hazardous to substance abuse treatment. Meanwhile, decreased stigmatization among cannabis users might occur because some people use cannabis without experiencing harm or believe it to be a harmless substance and might not be receiving treatment. Several studies have investigated stigma toward substance use disorder and treatment. However, less is known about how stigmatization influences treatment. Aims: To investigate the association between the perceived stigma of addiction and treatment utilization among cannabis addicts. Materials and Methods: A cross-sectional design was conducted with consecutive sampling techniques among 977 cannabis users recruited from all 7 compulsory drug detention centers in Thailand. The data were collected by standardized interviewers with a structured interviewing questionnaire. Binary logistic regression was applied to determine the effect of perceived stigma of treatment utilization. Results: Most clients were male (84.5%), had a family history of drug problems (54.5%), and had a history of mental health problems (5.1%). Most of them reported moderate-to-high levels of perceived stigma (87.2%) and received treatment (28.9%). Greater perceived stigma was associated with decreased treatment for cannabis abuse. Conclusions: The perceived stigma of addiction is a barrier to cannabis abuse treatment utilization. Thus, a better understanding of stigma could reduce its negative impact on seeking and engaging in treatment.

Evaluation of the amino acid composition, phytochemical properties and antioxidant activity of Coprinus radiata mushrooms was conducted. Free amino acid composition of fresh mushrooms was analyzed by LC-MS/MS. The phytochemical properties analysis included total phenolic compound content and total flavonoid content of these mushrooms. Furthermore, antioxidant activity assays were performed using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP). Based on the results shown that a high concentration of non-essential amino acids, especially those of arginine and glutamic acid, were observed. However, isoleucine and leucine were major essential amino acids in these mushrooms. The ethanolic extract of C. radiata showed higher phytochemical contents and antioxidant activity than those of the water extract. It suggested that the C. radiata is a natural source containing some essential amino acids, a high amount of phytochemical properties and high antioxidant activity, potentially having medicinal and nutritional properties that provide health benefits.